KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A25
All Species:
30
Human Site:
S420
Identified Species:
50.77
UniProt:
Q6KCM7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6KCM7
NP_001006642.1
469
52663
S420
G
A
P
E
V
T
M
S
S
L
F
K
H
I
L
Chimpanzee
Pan troglodytes
XP_001153366
469
52663
S420
G
A
P
E
V
T
M
S
S
L
F
K
H
I
L
Rhesus Macaque
Macaca mulatta
XP_001088378
468
52373
L419
G
G
P
Q
L
S
M
L
G
L
L
R
H
I
L
Dog
Lupus familis
XP_862510
469
52735
S420
G
A
P
E
V
T
M
S
S
L
F
R
Q
I
L
Cat
Felis silvestris
Mouse
Mus musculus
A2ASZ8
469
52602
S420
G
A
P
E
V
T
M
S
S
L
F
K
Q
I
L
Rat
Rattus norvegicus
Q8K3P6
469
52677
S420
G
A
P
E
V
T
M
S
S
L
F
K
Q
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505563
469
52720
S420
G
A
P
E
V
T
M
S
S
L
F
R
Q
I
L
Chicken
Gallus gallus
XP_415513
469
52817
R420
G
A
P
E
V
T
M
R
G
L
F
K
H
I
L
Frog
Xenopus laevis
Q7ZYD5
514
56789
S465
G
A
P
Q
M
T
M
S
K
L
F
K
H
I
V
Zebra Danio
Brachydanio rerio
A2CEQ0
469
52693
S420
G
S
P
Q
M
T
M
S
G
L
F
R
H
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20799
588
66319
M485
Y
S
P
Q
P
D
T
M
F
G
Q
F
K
Y
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P29518
436
46609
G387
G
A
G
G
L
Y
R
G
L
G
P
S
C
I
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65023
381
41798
R333
D
G
L
I
G
L
Y
R
G
F
L
P
N
A
L
Baker's Yeast
Sacchar. cerevisiae
P48233
545
61252
P491
A
Q
G
T
Y
A
H
P
Y
V
Y
N
G
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
63.7
97.8
N.A.
97.4
97
N.A.
96.3
93.5
76.2
85.7
N.A.
N.A.
N.A.
39.7
N.A.
Protein Similarity:
100
99.7
75.6
99.1
N.A.
98.7
98.7
N.A.
98.7
98
82.8
94
N.A.
N.A.
N.A.
58.1
N.A.
P-Site Identity:
100
100
46.6
86.6
N.A.
93.3
93.3
N.A.
86.6
86.6
73.3
60
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
73.3
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
93.3
93.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
28.3
N.A.
25.8
28.8
N.A.
Protein Similarity:
N.A.
45.4
N.A.
42.8
47.5
N.A.
P-Site Identity:
N.A.
20
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
65
0
0
0
8
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
65
8
0
8
0
% F
% Gly:
79
15
15
8
8
0
0
8
29
15
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
43
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
79
8
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
43
8
0
15
% K
% Leu:
0
0
8
0
15
8
0
8
8
72
15
0
0
0
65
% L
% Met:
0
0
0
0
15
0
72
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
79
0
8
0
0
8
0
0
8
8
0
0
0
% P
% Gln:
0
8
0
29
0
0
0
0
0
0
8
0
29
0
0
% Q
% Arg:
0
0
0
0
0
0
8
15
0
0
0
29
0
0
0
% R
% Ser:
0
15
0
0
0
8
0
58
43
0
0
8
0
0
0
% S
% Thr:
0
0
0
8
0
65
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
50
0
0
0
0
8
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
8
8
0
8
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _