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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A25 All Species: 36.36
Human Site: T429 Identified Species: 61.54
UniProt: Q6KCM7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6KCM7 NP_001006642.1 469 52663 T429 L F K H I L R T E G A F G L Y
Chimpanzee Pan troglodytes XP_001153366 469 52663 T429 L F K H I L R T E G A F G L Y
Rhesus Macaque Macaca mulatta XP_001088378 468 52373 Q428 L L R H I L S Q E G M R G L Y
Dog Lupus familis XP_862510 469 52735 T429 L F R Q I L R T E G A F G L Y
Cat Felis silvestris
Mouse Mus musculus A2ASZ8 469 52602 T429 L F K Q I L R T E G A F G L Y
Rat Rattus norvegicus Q8K3P6 469 52677 T429 L F K Q I L R T E G A F G L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505563 469 52720 T429 L F R Q I L R T E G A F G L Y
Chicken Gallus gallus XP_415513 469 52817 T429 L F K H I L K T E G A F G L Y
Frog Xenopus laevis Q7ZYD5 514 56789 T474 L F K H I V K T E G A F G L Y
Zebra Danio Brachydanio rerio A2CEQ0 469 52693 T429 L F R H I V R T E G A I G L Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20799 588 66319 Q494 G Q F K Y I L Q N E G V T G F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P29518 436 46609 M396 G P S C I K L M P A A G I A F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65023 381 41798 T342 F L P N A L K T L P N S S I R
Baker's Yeast Sacchar. cerevisiae P48233 545 61252 V500 V Y N G F K D V L L K T L E R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 63.7 97.8 N.A. 97.4 97 N.A. 96.3 93.5 76.2 85.7 N.A. N.A. N.A. 39.7 N.A.
Protein Similarity: 100 99.7 75.6 99.1 N.A. 98.7 98.7 N.A. 98.7 98 82.8 94 N.A. N.A. N.A. 58.1 N.A.
P-Site Identity: 100 100 60 86.6 N.A. 93.3 93.3 N.A. 86.6 93.3 86.6 80 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 66.6 93.3 N.A. 93.3 93.3 N.A. 93.3 100 100 93.3 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. 28.3 N.A. 25.8 28.8 N.A.
Protein Similarity: N.A. 45.4 N.A. 42.8 47.5 N.A.
P-Site Identity: N.A. 13.3 N.A. 13.3 0 N.A.
P-Site Similarity: N.A. 20 N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 8 72 0 0 8 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 72 8 0 0 0 8 0 % E
% Phe: 8 65 8 0 8 0 0 0 0 0 0 58 0 0 15 % F
% Gly: 15 0 0 8 0 0 0 0 0 72 8 8 72 8 0 % G
% His: 0 0 0 43 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 79 8 0 0 0 0 0 8 8 8 0 % I
% Lys: 0 0 43 8 0 15 22 0 0 0 8 0 0 0 0 % K
% Leu: 72 15 0 0 0 65 15 0 15 8 0 0 8 72 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 0 8 0 8 0 0 0 0 % N
% Pro: 0 8 8 0 0 0 0 0 8 8 0 0 0 0 0 % P
% Gln: 0 8 0 29 0 0 0 15 0 0 0 0 0 0 0 % Q
% Arg: 0 0 29 0 0 0 50 0 0 0 0 8 0 0 15 % R
% Ser: 0 0 8 0 0 0 8 0 0 0 0 8 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 72 0 0 0 8 8 0 0 % T
% Val: 8 0 0 0 0 15 0 8 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 72 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _