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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A25 All Species: 28.9
Human Site: Y7 Identified Species: 48.9
UniProt: Q6KCM7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6KCM7 NP_001006642.1 469 52663 Y7 _ M L C L C L Y V P V I G E A
Chimpanzee Pan troglodytes XP_001153366 469 52663 Y7 _ M L C L C L Y V P V I G E A
Rhesus Macaque Macaca mulatta XP_001088378 468 52373 A8 M R G S P G D A E R R Q R W G
Dog Lupus familis XP_862510 469 52735 Y7 _ M L C L C L Y V P L I G E T
Cat Felis silvestris
Mouse Mus musculus A2ASZ8 469 52602 Y7 _ M L C L C L Y V P I A G A A
Rat Rattus norvegicus Q8K3P6 469 52677 Y7 _ M L C L C L Y V P I A G E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505563 469 52720 Y7 _ M L C L C L Y V P V F G E A
Chicken Gallus gallus XP_415513 469 52817 Y7 _ M L C L C L Y V P V L G Q S
Frog Xenopus laevis Q7ZYD5 514 56789 C52 D P C G G L L C G G P E H E R
Zebra Danio Brachydanio rerio A2CEQ0 469 52693 Y7 _ M L C L C L Y V P V H I S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20799 588 66319 V50 S P K H V P L V L G K V T K E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P29518 436 46609
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65023 381 41798
Baker's Yeast Sacchar. cerevisiae P48233 545 61252 F20 D I R Y A C L F K E L D V K G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 63.7 97.8 N.A. 97.4 97 N.A. 96.3 93.5 76.2 85.7 N.A. N.A. N.A. 39.7 N.A.
Protein Similarity: 100 99.7 75.6 99.1 N.A. 98.7 98.7 N.A. 98.7 98 82.8 94 N.A. N.A. N.A. 58.1 N.A.
P-Site Identity: 100 100 0 85.7 N.A. 78.5 85.7 N.A. 92.8 78.5 13.3 71.4 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 0 92.8 N.A. 85.7 92.8 N.A. 92.8 100 13.3 71.4 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. 28.3 N.A. 25.8 28.8 N.A.
Protein Similarity: N.A. 45.4 N.A. 42.8 47.5 N.A.
P-Site Identity: N.A. 0 N.A. 0 13.3 N.A.
P-Site Similarity: N.A. 0 N.A. 0 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 0 0 0 15 0 8 36 % A
% Cys: 0 0 8 58 0 65 0 8 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 8 0 8 0 43 15 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % F
% Gly: 0 0 8 8 8 8 0 0 8 15 0 0 50 0 15 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 8 8 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 15 22 8 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 8 0 8 0 0 15 0 % K
% Leu: 0 0 58 0 58 8 79 0 8 0 15 8 0 0 0 % L
% Met: 8 58 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 15 0 0 8 8 0 0 0 58 8 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % Q
% Arg: 0 8 8 0 0 0 0 0 0 8 8 0 8 0 8 % R
% Ser: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % T
% Val: 0 0 0 0 8 0 0 8 58 0 36 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 8 0 0 0 58 0 0 0 0 0 0 0 % Y
% Spaces: 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _