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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF6
All Species:
9.39
Human Site:
S174
Identified Species:
18.79
UniProt:
Q6KF10
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6KF10
NP_001001557.1
455
50662
S174
R
L
F
R
Q
A
P
S
A
P
W
G
P
P
A
Chimpanzee
Pan troglodytes
XP_001164592
501
55399
S247
R
I
L
R
K
K
P
S
D
T
A
K
P
A
A
Rhesus Macaque
Macaca mulatta
XP_001090825
455
50711
S174
R
L
F
R
Q
A
P
S
A
P
W
G
P
P
A
Dog
Lupus familis
XP_542974
499
55131
S245
R
I
L
R
K
K
P
S
D
T
A
K
P
V
A
Cat
Felis silvestris
Mouse
Mus musculus
P43028
454
50923
P177
R
L
Y
R
Q
A
P
P
T
P
W
G
L
P
A
Rat
Rattus norvegicus
Q6HA10
452
50994
P175
R
L
Y
R
Q
A
P
P
T
P
W
G
P
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511410
181
19862
Chicken
Gallus gallus
Q90752
405
46039
E167
R
L
Y
R
E
Q
V
E
E
P
S
A
A
W
E
Frog
Xenopus laevis
P25703
398
45557
Q160
R
I
F
R
E
Q
V
Q
E
P
F
E
S
D
S
Zebra Danio
Brachydanio rerio
P85857
404
46271
G151
R
I
F
R
K
S
P
G
D
V
Q
P
S
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
L231
V
E
I
E
K
S
L
L
S
L
F
N
M
K
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48969
461
51863
P191
R
F
D
I
G
R
I
P
Q
G
E
T
V
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.9
98
33.6
N.A.
87.6
86.1
N.A.
31.2
29.6
28.3
55.8
N.A.
23.9
N.A.
N.A.
23.4
Protein Similarity:
100
47.3
98.4
45.6
N.A.
90.5
89.4
N.A.
36
46.1
47.6
67
N.A.
41.5
N.A.
N.A.
37.9
P-Site Identity:
100
40
100
40
N.A.
73.3
66.6
N.A.
0
26.6
26.6
33.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
53.3
100
53.3
N.A.
80
73.3
N.A.
0
40
53.3
60
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
34
0
0
17
0
17
9
9
9
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
25
0
0
0
0
9
0
% D
% Glu:
0
9
0
9
17
0
0
9
17
0
9
9
0
0
9
% E
% Phe:
0
9
34
0
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
9
0
9
0
34
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
34
9
9
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
34
17
0
0
0
0
0
17
0
9
0
% K
% Leu:
0
42
17
0
0
0
9
9
0
9
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
59
25
0
50
0
9
42
34
0
% P
% Gln:
0
0
0
0
34
17
0
9
9
0
9
0
0
9
0
% Q
% Arg:
84
0
0
75
0
9
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
0
0
17
0
34
9
0
9
0
17
0
25
% S
% Thr:
0
0
0
0
0
0
0
0
17
17
0
9
0
9
9
% T
% Val:
9
0
0
0
0
0
17
0
0
9
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
34
0
0
9
0
% W
% Tyr:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _