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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF6
All Species:
14.85
Human Site:
S262
Identified Species:
29.7
UniProt:
Q6KF10
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6KF10
NP_001001557.1
455
50662
S262
P
P
P
P
D
L
R
S
L
G
F
G
R
R
V
Chimpanzee
Pan troglodytes
XP_001164592
501
55399
N302
D
I
W
K
L
F
R
N
F
K
N
S
A
Q
L
Rhesus Macaque
Macaca mulatta
XP_001090825
455
50711
S262
P
P
P
P
D
L
R
S
L
G
F
G
R
R
V
Dog
Lupus familis
XP_542974
499
55131
N300
D
I
W
K
L
F
R
N
F
K
N
S
A
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
P43028
454
50923
S265
P
P
P
L
D
L
R
S
L
G
F
G
R
R
V
Rat
Rattus norvegicus
Q6HA10
452
50994
S263
S
P
P
L
D
L
R
S
L
G
F
G
R
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511410
181
19862
Chicken
Gallus gallus
Q90752
405
46039
W224
V
S
P
A
V
I
R
W
T
K
D
K
Q
P
N
Frog
Xenopus laevis
P25703
398
45557
W218
V
T
P
A
I
A
R
W
I
A
H
K
Q
P
N
Zebra Danio
Brachydanio rerio
P85857
404
46271
K212
N
Q
L
C
L
Q
L
K
V
T
Y
G
K
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
S311
R
L
H
F
D
V
K
S
I
P
A
D
E
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48969
461
51863
A243
L
D
S
T
I
V
G
A
G
D
H
G
W
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.9
98
33.6
N.A.
87.6
86.1
N.A.
31.2
29.6
28.3
55.8
N.A.
23.9
N.A.
N.A.
23.4
Protein Similarity:
100
47.3
98.4
45.6
N.A.
90.5
89.4
N.A.
36
46.1
47.6
67
N.A.
41.5
N.A.
N.A.
37.9
P-Site Identity:
100
6.6
100
6.6
N.A.
93.3
86.6
N.A.
0
13.3
13.3
6.6
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
100
26.6
N.A.
93.3
86.6
N.A.
0
26.6
26.6
26.6
N.A.
46.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
9
0
9
0
9
9
0
17
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
0
0
42
0
0
0
0
9
9
9
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
9
0
17
0
0
17
0
34
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
9
34
0
50
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
17
0
0
0
0
% H
% Ile:
0
17
0
0
17
9
0
0
17
0
0
0
0
0
0
% I
% Lys:
0
0
0
17
0
0
9
9
0
25
0
17
9
9
0
% K
% Leu:
9
9
9
17
25
34
9
0
34
0
0
0
0
9
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
17
0
0
17
0
0
0
17
% N
% Pro:
25
34
50
17
0
0
0
0
0
9
0
0
0
17
0
% P
% Gln:
0
9
0
0
0
9
0
0
0
0
0
0
17
17
0
% Q
% Arg:
9
0
0
0
0
0
67
0
0
0
0
0
34
34
0
% R
% Ser:
9
9
9
0
0
0
0
42
0
0
0
17
0
9
0
% S
% Thr:
0
9
0
9
0
0
0
0
9
9
0
0
0
0
0
% T
% Val:
17
0
0
0
9
17
0
0
9
0
0
0
0
0
42
% V
% Trp:
0
0
17
0
0
0
0
17
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _