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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE12
All Species:
22.12
Human Site:
S28
Identified Species:
34.76
UniProt:
Q6L8Q7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6L8Q7
NP_808881.3
609
67352
S28
L
S
R
A
E
A
G
S
Q
T
A
A
G
A
M
Chimpanzee
Pan troglodytes
XP_517033
609
67371
S28
L
S
R
A
E
A
E
S
Q
T
A
A
G
A
M
Rhesus Macaque
Macaca mulatta
XP_001099328
609
67247
S28
L
S
P
A
E
A
Q
S
Q
T
A
A
G
A
M
Dog
Lupus familis
XP_541830
616
67598
T31
A
E
A
A
A
A
A
T
E
T
A
A
G
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q3TIU4
608
67495
T27
R
S
R
A
E
A
G
T
H
E
A
V
R
A
M
Rat
Rattus norvegicus
Q6AXQ5
608
67158
T27
R
S
P
A
E
A
T
T
H
E
A
V
R
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511095
639
68679
S29
V
A
A
R
R
S
G
S
R
R
G
G
A
A
M
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038753
591
65883
S20
F
F
R
F
I
P
P
S
L
I
P
P
R
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723735
564
64146
F19
T
K
E
L
D
I
V
F
R
F
V
N
E
N
L
Honey Bee
Apis mellifera
XP_001121328
441
50969
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784408
1354
152949
T248
V
A
N
L
N
S
S
T
P
M
T
L
N
A
R
Poplar Tree
Populus trichocarpa
XP_002323345
603
66902
T35
R
P
D
T
N
A
T
T
D
D
V
P
E
S
A
Maize
Zea mays
NP_001146094
605
67010
R27
I
T
P
Y
V
L
L
R
R
P
D
G
A
V
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F8
603
67035
N32
L
V
R
R
P
D
K
N
S
T
T
D
D
V
P
Baker's Yeast
Sacchar. cerevisiae
P31384
837
94681
Q193
Y
L
A
T
Q
Q
A
Q
Q
A
Q
Q
Q
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.8
92.3
N.A.
88.3
89.8
N.A.
74.3
N.A.
N.A.
54.6
N.A.
33.9
29.3
N.A.
20.3
Protein Similarity:
100
99.1
99.1
95.9
N.A.
92.2
93
N.A.
82.3
N.A.
N.A.
71
N.A.
51
45.3
N.A.
30.6
P-Site Identity:
100
93.3
86.6
53.3
N.A.
60
46.6
N.A.
26.6
N.A.
N.A.
13.3
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
93.3
86.6
66.6
N.A.
66.6
53.3
N.A.
53.3
N.A.
N.A.
13.3
N.A.
20
0
N.A.
33.3
Percent
Protein Identity:
25.4
25.2
N.A.
25.9
21.1
N.A.
Protein Similarity:
41.8
43.1
N.A.
42.6
34.7
N.A.
P-Site Identity:
6.6
0
N.A.
20
13.3
N.A.
P-Site Similarity:
20
20
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
14
20
40
7
47
14
0
0
7
40
27
14
60
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
7
0
0
7
7
7
7
7
0
0
% D
% Glu:
0
7
7
0
34
0
7
0
7
14
0
0
14
0
0
% E
% Phe:
7
7
0
7
0
0
0
7
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
20
0
0
0
7
14
27
0
0
% G
% His:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
7
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
27
7
0
14
0
7
7
0
7
0
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
47
% M
% Asn:
0
0
7
0
14
0
0
7
0
0
0
7
7
7
7
% N
% Pro:
0
7
20
0
7
7
7
0
7
7
7
14
0
0
7
% P
% Gln:
0
0
0
0
7
7
7
7
27
0
7
7
7
0
7
% Q
% Arg:
20
0
34
14
7
0
0
7
20
7
0
0
20
7
7
% R
% Ser:
0
34
0
0
0
14
7
34
7
0
0
0
0
7
7
% S
% Thr:
7
7
0
14
0
0
14
34
0
34
14
0
0
0
0
% T
% Val:
14
7
0
0
7
0
7
0
0
0
14
14
0
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _