KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE12
All Species:
18.48
Human Site:
S423
Identified Species:
29.05
UniProt:
Q6L8Q7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6L8Q7
NP_808881.3
609
67352
S423
E
K
L
V
L
Y
P
S
A
Q
E
K
V
L
Q
Chimpanzee
Pan troglodytes
XP_517033
609
67371
S423
E
K
L
V
L
Y
P
S
A
Q
E
K
V
L
Q
Rhesus Macaque
Macaca mulatta
XP_001099328
609
67247
S423
E
K
L
V
L
Y
P
S
A
Q
E
K
V
L
Q
Dog
Lupus familis
XP_541830
616
67598
S430
E
K
L
V
V
Y
P
S
A
Q
E
R
V
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3TIU4
608
67495
L422
E
K
L
A
L
N
P
L
A
Q
E
K
V
L
Q
Rat
Rattus norvegicus
Q6AXQ5
608
67158
L422
E
K
L
A
L
N
P
L
A
Q
E
K
V
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511095
639
68679
L453
E
K
L
S
P
Y
P
L
V
R
E
K
V
L
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038753
591
65883
S401
E
K
V
S
C
S
P
S
L
K
E
K
I
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723735
564
64146
I388
L
Q
T
C
L
L
R
I
K
G
T
D
N
Y
V
Honey Bee
Apis mellifera
XP_001121328
441
50969
I265
R
N
T
I
I
Q
L
I
V
L
R
S
K
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784408
1354
152949
A1159
E
A
V
S
K
S
P
A
M
L
N
Q
V
L
T
Poplar Tree
Populus trichocarpa
XP_002323345
603
66902
G412
N
Q
G
A
D
N
P
G
K
R
Q
L
L
C
V
Maize
Zea mays
NP_001146094
605
67010
G414
N
H
G
A
E
N
P
G
K
R
Q
L
L
C
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F8
603
67035
S409
G
N
Q
P
T
D
P
S
G
K
R
Q
L
I
C
Baker's Yeast
Sacchar. cerevisiae
P31384
837
94681
N640
D
Y
L
N
R
A
M
N
K
D
N
V
A
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.8
92.3
N.A.
88.3
89.8
N.A.
74.3
N.A.
N.A.
54.6
N.A.
33.9
29.3
N.A.
20.3
Protein Similarity:
100
99.1
99.1
95.9
N.A.
92.2
93
N.A.
82.3
N.A.
N.A.
71
N.A.
51
45.3
N.A.
30.6
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
66.6
N.A.
N.A.
40
N.A.
6.6
0
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
73.3
N.A.
N.A.
66.6
N.A.
13.3
13.3
N.A.
46.6
Percent
Protein Identity:
25.4
25.2
N.A.
25.9
21.1
N.A.
Protein Similarity:
41.8
43.1
N.A.
42.6
34.7
N.A.
P-Site Identity:
6.6
6.6
N.A.
13.3
13.3
N.A.
P-Site Similarity:
33.3
26.6
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
27
0
7
0
7
40
0
0
0
7
0
0
% A
% Cys:
0
0
0
7
7
0
0
0
0
0
0
0
0
14
7
% C
% Asp:
7
0
0
0
7
7
0
0
0
7
0
7
0
0
0
% D
% Glu:
60
0
0
0
7
0
0
0
0
0
54
0
0
14
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
7
0
14
0
0
0
0
14
7
7
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
7
0
0
14
0
0
0
0
7
7
0
% I
% Lys:
0
54
0
0
7
0
0
0
27
14
0
47
7
0
7
% K
% Leu:
7
0
54
0
40
7
7
20
7
14
0
14
20
60
0
% L
% Met:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% M
% Asn:
14
14
0
7
0
27
0
7
0
0
14
0
7
0
7
% N
% Pro:
0
0
0
7
7
0
80
0
0
0
0
0
0
0
0
% P
% Gln:
0
14
7
0
0
7
0
0
0
40
14
14
0
0
47
% Q
% Arg:
7
0
0
0
7
0
7
0
0
20
14
7
0
0
0
% R
% Ser:
0
0
0
20
0
14
0
40
0
0
0
7
0
0
0
% S
% Thr:
0
0
14
0
7
0
0
0
0
0
7
0
0
0
7
% T
% Val:
0
0
14
27
7
0
0
0
14
0
0
7
54
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
34
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _