KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE12
All Species:
27.58
Human Site:
Y126
Identified Species:
43.33
UniProt:
Q6L8Q7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6L8Q7
NP_808881.3
609
67352
Y126
C
E
P
V
V
K
L
Y
Y
R
E
E
A
V
A
Chimpanzee
Pan troglodytes
XP_517033
609
67371
Y126
C
E
P
V
V
K
L
Y
Y
R
E
E
A
V
A
Rhesus Macaque
Macaca mulatta
XP_001099328
609
67247
Y126
C
E
P
V
V
K
L
Y
Y
R
E
E
A
V
A
Dog
Lupus familis
XP_541830
616
67598
Y133
C
E
P
V
V
K
L
Y
Y
R
E
E
A
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TIU4
608
67495
Y125
C
E
P
V
V
K
L
Y
Y
R
E
E
A
V
A
Rat
Rattus norvegicus
Q6AXQ5
608
67158
Y125
C
E
P
V
V
K
L
Y
Y
R
E
E
A
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511095
639
68679
Y137
G
G
P
L
V
R
L
Y
Y
R
E
E
A
V
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038753
591
65883
N116
P
E
T
S
L
S
V
N
G
Q
P
V
S
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723735
564
64146
F115
D
T
V
Y
D
L
V
F
N
P
P
W
I
S
S
Honey Bee
Apis mellifera
XP_001121328
441
50969
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784408
1354
152949
D686
S
P
V
A
L
D
I
D
Y
R
E
Q
L
L
L
Poplar Tree
Populus trichocarpa
XP_002323345
603
66902
N131
E
E
L
F
G
R
F
N
S
S
G
S
G
V
M
Maize
Zea mays
NP_001146094
605
67010
F127
G
A
E
E
E
E
L
F
G
R
F
G
S
G
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F8
603
67035
S129
D
D
L
N
R
N
N
S
A
G
S
G
S
L
A
Baker's Yeast
Sacchar. cerevisiae
P31384
837
94681
F291
L
T
P
K
I
E
L
F
A
N
G
K
D
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.8
92.3
N.A.
88.3
89.8
N.A.
74.3
N.A.
N.A.
54.6
N.A.
33.9
29.3
N.A.
20.3
Protein Similarity:
100
99.1
99.1
95.9
N.A.
92.2
93
N.A.
82.3
N.A.
N.A.
71
N.A.
51
45.3
N.A.
30.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
66.6
N.A.
N.A.
6.6
N.A.
0
0
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
N.A.
N.A.
33.3
N.A.
20
0
N.A.
46.6
Percent
Protein Identity:
25.4
25.2
N.A.
25.9
21.1
N.A.
Protein Similarity:
41.8
43.1
N.A.
42.6
34.7
N.A.
P-Site Identity:
13.3
13.3
N.A.
6.6
20
N.A.
P-Site Similarity:
20
33.3
N.A.
26.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
0
14
0
0
0
47
0
54
% A
% Cys:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
0
0
7
7
0
7
0
0
0
0
7
0
0
% D
% Glu:
7
54
7
7
7
14
0
0
0
0
54
47
0
7
7
% E
% Phe:
0
0
0
7
0
0
7
20
0
0
7
0
0
0
0
% F
% Gly:
14
7
0
0
7
0
0
0
14
7
14
14
7
7
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
7
0
0
0
0
0
7
0
0
% I
% Lys:
0
0
0
7
0
40
0
0
0
0
0
7
0
0
0
% K
% Leu:
7
0
14
7
14
7
60
0
0
0
0
0
7
14
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
7
0
7
7
14
7
7
0
0
0
0
0
% N
% Pro:
7
7
54
0
0
0
0
0
0
7
14
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% Q
% Arg:
0
0
0
0
7
14
0
0
0
60
0
0
0
0
0
% R
% Ser:
7
0
0
7
0
7
0
7
7
7
7
7
20
7
7
% S
% Thr:
0
14
7
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
14
40
47
0
14
0
0
0
0
7
0
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
47
54
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _