KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEPHL1
All Species:
27.58
Human Site:
Y74
Identified Species:
75.83
UniProt:
Q6MZM0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6MZM0
NP_001092142.1
1159
131603
Y74
P
N
R
I
G
S
I
Y
K
K
A
V
Y
R
R
Chimpanzee
Pan troglodytes
XP_508699
1298
146493
Y213
P
N
R
I
G
S
I
Y
K
K
A
V
Y
R
R
Rhesus Macaque
Macaca mulatta
XP_001086917
1202
135990
Y117
P
N
R
I
G
G
I
Y
K
K
A
V
Y
R
H
Dog
Lupus familis
XP_542245
1160
131714
Y74
P
N
R
I
G
G
L
Y
K
K
A
V
Y
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3V1H3
1159
130869
Y73
P
N
R
I
G
G
I
Y
K
K
A
V
Y
R
H
Rat
Rattus norvegicus
Q920H8
1157
129575
Y73
K
N
R
I
G
G
T
Y
K
K
T
V
Y
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513275
1390
155965
Y222
P
N
R
V
G
S
V
Y
K
K
A
V
Y
K
H
Chicken
Gallus gallus
XP_417192
1151
128613
T75
F
R
Q
Y
T
D
D
T
Y
S
Q
E
I
P
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571877
1087
124540
Y70
E
Q
R
I
G
R
V
Y
K
K
A
V
Y
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
93.9
90
N.A.
87.3
49.9
N.A.
65.3
59.6
N.A.
48.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
89.1
95.4
94.6
N.A.
93.7
67.2
N.A.
73.8
75.4
N.A.
64.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
80
N.A.
86.6
60
N.A.
73.3
0
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
86.6
N.A.
86.6
66.6
N.A.
93.3
13.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
78
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
89
45
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
45
% H
% Ile:
0
0
0
78
0
0
45
0
0
0
0
0
12
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
89
89
0
0
0
23
12
% K
% Leu:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
78
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
67
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
0
12
12
0
0
0
0
0
0
0
12
0
0
0
12
% Q
% Arg:
0
12
89
0
0
12
0
0
0
0
0
0
0
56
23
% R
% Ser:
0
0
0
0
0
34
0
0
0
12
0
0
0
0
0
% S
% Thr:
0
0
0
0
12
0
12
12
0
0
12
0
0
0
0
% T
% Val:
0
0
0
12
0
0
23
0
0
0
0
89
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
89
12
0
0
0
89
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _