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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIN54 All Species: 15.45
Human Site: S493 Identified Species: 37.78
UniProt: Q6MZP7 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6MZP7 NP_001108479.1 749 79467 S493 Y V S I A S N S T F T G T S G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001102124 508 55078 L281 T Q Q L E G A L P S V V N G S
Dog Lupus familis XP_535631 767 81588 S511 Y V S I A S N S N F T G T P G
Cat Felis silvestris
Mouse Mus musculus Q571G4 749 79548 S493 Y V S I A S N S N F T G T S G
Rat Rattus norvegicus Q641Z1 749 79242 S493 Y V S I A G N S N F T G T S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516542 328 34146 A101 P N P T V I S A F P G G L P K
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08CM4 771 81370 S516 F V T L T S S S T F S T A T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1Z9E2 950 100003 R585 N R T A N V Q R V V S S S T S
Honey Bee Apis mellifera XP_392991 821 88529 A503 N Q S L R T V A P K A T L T G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792482 689 72067 D462 L N N L D H E D E R T K A V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 30.5 96.6 N.A. 96.5 95.4 N.A. 34.8 N.A. N.A. 53.7 N.A. 28.3 33.5 N.A. 35.6
Protein Similarity: 100 N.A. 43.2 97.1 N.A. 98 97.1 N.A. 38.1 N.A. N.A. 67.3 N.A. 43.6 48.5 N.A. 50.8
P-Site Identity: 100 N.A. 0 86.6 N.A. 93.3 86.6 N.A. 6.6 N.A. N.A. 33.3 N.A. 0 13.3 N.A. 6.6
P-Site Similarity: 100 N.A. 6.6 86.6 N.A. 93.3 86.6 N.A. 20 N.A. N.A. 73.3 N.A. 26.6 40 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 40 0 10 20 0 0 10 0 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 10 0 10 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 10 50 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 20 0 0 0 0 10 50 0 10 50 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 40 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 20 % K
% Leu: 10 0 0 40 0 0 0 10 0 0 0 0 20 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 20 20 10 0 10 0 40 0 30 0 0 0 10 0 0 % N
% Pro: 10 0 10 0 0 0 0 0 20 10 0 0 0 20 10 % P
% Gln: 0 20 10 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 10 0 0 10 0 10 0 0 0 0 0 % R
% Ser: 0 0 50 0 0 40 20 50 0 10 20 10 10 30 20 % S
% Thr: 10 0 20 10 10 10 0 0 20 0 50 20 40 30 0 % T
% Val: 0 50 0 0 10 10 10 0 10 10 10 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _