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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD5
All Species:
18.18
Human Site:
S233
Identified Species:
36.36
UniProt:
Q6N075
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6N075
NP_116278.2
450
49765
S233
Y
D
R
Q
R
A
F
S
R
T
C
A
G
G
L
Chimpanzee
Pan troglodytes
XP_522401
576
63600
S359
Y
D
R
Q
R
A
F
S
R
T
C
A
G
G
L
Rhesus Macaque
Macaca mulatta
XP_001103099
450
49788
S233
Y
D
R
Q
R
A
F
S
R
T
C
A
G
G
L
Dog
Lupus familis
XP_849836
422
46499
V205
L
G
P
V
A
P
F
V
A
A
I
P
L
L
A
Cat
Felis silvestris
Mouse
Mus musculus
NP_598861
450
49661
S233
Y
D
R
Q
R
A
F
S
K
T
C
A
G
G
L
Rat
Rattus norvegicus
NP_001119754
450
49665
S233
Y
D
R
Q
R
A
F
S
K
T
C
A
G
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002713
481
52771
W260
L
S
A
R
A
R
F
W
R
S
C
V
D
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500274
432
48048
N216
I
M
N
T
W
P
E
N
Y
G
N
E
K
A
P
Sea Urchin
Strong. purpuratus
XP_780162
453
49913
R237
K
E
N
Y
S
Q
Q
R
V
S
C
S
K
T
C
Poplar Tree
Populus trichocarpa
XP_002304575
443
48633
M216
A
I
G
M
A
I
I
M
S
S
W
T
E
N
Y
Maize
Zea mays
NP_001149961
458
50052
Q235
E
S
K
D
L
M
A
Q
F
K
V
A
A
K
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567786
460
50867
A244
R
G
A
A
V
A
I
A
S
D
E
K
I
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
99.3
90.4
N.A.
96.2
96
N.A.
N.A.
N.A.
N.A.
58.4
N.A.
N.A.
N.A.
33.7
49.2
Protein Similarity:
100
77.9
99.5
91.7
N.A.
98
98.2
N.A.
N.A.
N.A.
N.A.
71.7
N.A.
N.A.
N.A.
54.2
71
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
6.6
26.6
Percent
Protein Identity:
37.3
35.5
N.A.
36.7
N.A.
N.A.
Protein Similarity:
57.1
56.9
N.A.
55.8
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
6.6
13.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
9
25
50
9
9
9
9
0
50
9
17
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
59
0
0
0
9
% C
% Asp:
0
42
0
9
0
0
0
0
0
9
0
0
9
0
0
% D
% Glu:
9
9
0
0
0
0
9
0
0
0
9
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
59
0
9
0
0
0
0
0
0
% F
% Gly:
0
17
9
0
0
0
0
0
0
9
0
0
42
50
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
0
9
17
0
0
0
9
0
9
0
0
% I
% Lys:
9
0
9
0
0
0
0
0
17
9
0
9
17
9
0
% K
% Leu:
17
0
0
0
9
0
0
0
0
0
0
0
9
9
59
% L
% Met:
0
9
0
9
0
9
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
0
9
0
0
9
0
0
9
0
% N
% Pro:
0
0
9
0
0
17
0
0
0
0
0
9
0
0
9
% P
% Gln:
0
0
0
42
0
9
9
9
0
0
0
0
0
0
0
% Q
% Arg:
9
0
42
9
42
9
0
9
34
0
0
0
0
0
0
% R
% Ser:
0
17
0
0
9
0
0
42
17
25
0
9
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
0
0
42
0
9
0
9
0
% T
% Val:
0
0
0
9
9
0
0
9
9
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
9
0
0
9
0
0
9
0
0
0
0
% W
% Tyr:
42
0
0
9
0
0
0
0
9
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _