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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD5
All Species:
23.33
Human Site:
S440
Identified Species:
46.67
UniProt:
Q6N075
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6N075
NP_116278.2
450
49765
S440
D
A
E
L
R
V
P
S
P
T
E
E
P
Y
A
Chimpanzee
Pan troglodytes
XP_522401
576
63600
S566
D
A
E
L
R
V
P
S
P
T
E
E
P
Y
A
Rhesus Macaque
Macaca mulatta
XP_001103099
450
49788
S440
D
A
E
L
R
V
P
S
P
T
E
E
P
Y
A
Dog
Lupus familis
XP_849836
422
46499
S412
N
A
E
L
R
V
P
S
P
T
G
E
P
Y
A
Cat
Felis silvestris
Mouse
Mus musculus
NP_598861
450
49661
S440
D
A
E
L
R
V
P
S
P
T
G
E
P
Y
A
Rat
Rattus norvegicus
NP_001119754
450
49665
S440
D
A
E
L
R
V
P
S
P
T
G
E
P
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002713
481
52771
D467
L
F
T
V
G
R
N
D
A
D
L
R
L
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500274
432
48048
P423
T
P
R
H
Q
K
L
P
I
S
V
E
E
A
E
Sea Urchin
Strong. purpuratus
XP_780162
453
49913
D444
K
N
D
S
A
L
K
D
D
G
G
D
N
G
E
Poplar Tree
Populus trichocarpa
XP_002304575
443
48633
L423
F
G
M
C
S
V
F
L
F
V
A
S
L
L
Q
Maize
Zea mays
NP_001149961
458
50052
S442
V
S
D
Q
V
H
K
S
S
T
K
A
Q
E
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567786
460
50867
R451
D
W
T
P
L
E
E
R
N
T
E
E
D
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
99.3
90.4
N.A.
96.2
96
N.A.
N.A.
N.A.
N.A.
58.4
N.A.
N.A.
N.A.
33.7
49.2
Protein Similarity:
100
77.9
99.5
91.7
N.A.
98
98.2
N.A.
N.A.
N.A.
N.A.
71.7
N.A.
N.A.
N.A.
54.2
71
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
37.3
35.5
N.A.
36.7
N.A.
N.A.
Protein Similarity:
57.1
56.9
N.A.
55.8
N.A.
N.A.
P-Site Identity:
6.6
13.3
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
6.6
33.3
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
9
0
0
0
9
0
9
9
0
9
50
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
17
0
0
0
0
17
9
9
0
9
9
0
0
% D
% Glu:
0
0
50
0
0
9
9
0
0
0
34
67
9
17
17
% E
% Phe:
9
9
0
0
0
0
9
0
9
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
9
0
0
0
0
9
34
0
0
9
9
% G
% His:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
9
17
0
0
0
9
0
0
0
0
% K
% Leu:
9
0
0
50
9
9
9
9
0
0
9
0
17
9
9
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
9
0
0
0
0
9
0
9
0
0
0
9
0
0
% N
% Pro:
0
9
0
9
0
0
50
9
50
0
0
0
50
9
0
% P
% Gln:
0
0
0
9
9
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
0
0
9
0
50
9
0
9
0
0
0
9
0
0
0
% R
% Ser:
0
9
0
9
9
0
0
59
9
9
0
9
0
0
0
% S
% Thr:
9
0
17
0
0
0
0
0
0
67
0
0
0
0
0
% T
% Val:
9
0
0
9
9
59
0
0
0
9
9
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _