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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD5
All Species:
18.79
Human Site:
Y299
Identified Species:
37.58
UniProt:
Q6N075
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6N075
NP_116278.2
450
49765
Y299
S
L
L
G
S
S
L
Y
R
I
A
T
S
K
R
Chimpanzee
Pan troglodytes
XP_522401
576
63600
Y425
S
L
L
G
S
S
L
Y
R
I
A
T
S
K
R
Rhesus Macaque
Macaca mulatta
XP_001103099
450
49788
Y299
S
L
L
G
S
S
L
Y
R
I
A
T
S
K
R
Dog
Lupus familis
XP_849836
422
46499
T271
F
I
F
V
F
L
W
T
P
V
L
D
P
H
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_598861
450
49661
Y299
S
L
L
G
S
S
L
Y
R
I
A
T
S
K
R
Rat
Rattus norvegicus
NP_001119754
450
49665
Y299
S
L
L
G
S
S
L
Y
R
I
A
T
S
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002713
481
52771
F326
T
M
A
G
S
T
L
F
R
L
A
T
S
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500274
432
48048
A282
I
P
H
G
Y
I
F
A
A
F
M
V
A
T
M
Sea Urchin
Strong. purpuratus
XP_780162
453
49913
G303
F
M
L
C
I
M
I
G
S
A
V
Y
Q
I
L
Poplar Tree
Populus trichocarpa
XP_002304575
443
48633
P282
S
P
N
G
E
D
I
P
H
G
F
I
F
A
T
Maize
Zea mays
NP_001149961
458
50052
A301
S
M
L
G
S
S
I
A
S
R
L
L
A
R
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567786
460
50867
P310
R
L
L
S
R
S
T
P
K
V
E
S
Y
M
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
99.3
90.4
N.A.
96.2
96
N.A.
N.A.
N.A.
N.A.
58.4
N.A.
N.A.
N.A.
33.7
49.2
Protein Similarity:
100
77.9
99.5
91.7
N.A.
98
98.2
N.A.
N.A.
N.A.
N.A.
71.7
N.A.
N.A.
N.A.
54.2
71
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
37.3
35.5
N.A.
36.7
N.A.
N.A.
Protein Similarity:
57.1
56.9
N.A.
55.8
N.A.
N.A.
P-Site Identity:
13.3
33.3
N.A.
20
N.A.
N.A.
P-Site Similarity:
20
60
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
17
9
9
50
0
17
17
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
17
0
9
0
9
0
9
9
0
9
9
0
9
0
0
% F
% Gly:
0
0
0
75
0
0
0
9
0
9
0
0
0
0
9
% G
% His:
0
0
9
0
0
0
0
0
9
0
0
0
0
9
0
% H
% Ile:
9
9
0
0
9
9
25
0
0
42
0
9
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
0
0
42
0
% K
% Leu:
0
50
67
0
0
9
50
0
0
9
17
9
0
0
9
% L
% Met:
0
25
0
0
0
9
0
0
0
0
9
0
0
9
9
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
17
0
0
0
0
0
17
9
0
0
0
9
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
9
0
0
0
9
0
0
0
50
9
0
0
0
9
42
% R
% Ser:
59
0
0
9
59
59
0
0
17
0
0
9
50
0
0
% S
% Thr:
9
0
0
0
0
9
9
9
0
0
0
50
0
9
9
% T
% Val:
0
0
0
9
0
0
0
0
0
17
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
42
0
0
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _