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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALKBH2
All Species:
13.94
Human Site:
S146
Identified Species:
38.33
UniProt:
Q6NS38
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NS38
NP_001001655.1
261
29322
S146
E
R
I
R
D
H
V
S
G
V
T
G
Q
T
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104262
261
29422
S146
E
R
I
R
D
R
V
S
G
V
T
G
Q
T
F
Dog
Lupus familis
XP_534719
259
29092
S144
E
H
V
R
D
R
V
S
V
V
T
G
E
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6P6J4
239
27111
C124
E
R
V
R
D
R
V
C
E
V
T
G
Q
T
F
Rat
Rattus norvegicus
Q5XIC8
295
33993
E166
W
T
L
K
S
R
I
E
E
N
T
G
H
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508166
269
30627
S154
E
R
I
R
D
R
V
S
R
A
T
G
H
N
F
Chicken
Gallus gallus
XP_415188
241
27997
V125
N
H
I
R
D
R
L
V
L
E
T
G
H
T
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697761
258
30075
T136
E
H
I
R
D
A
V
T
K
A
T
G
Y
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797704
265
30701
Q150
L
E
I
R
D
Q
I
Q
E
V
T
G
Y
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.6
81.6
N.A.
75.4
29.1
N.A.
66.1
61.6
N.A.
56.3
N.A.
N.A.
N.A.
N.A.
48.6
Protein Similarity:
100
N.A.
98.4
87.7
N.A.
81.6
41.3
N.A.
77.3
73.5
N.A.
70.5
N.A.
N.A.
N.A.
N.A.
64.5
P-Site Identity:
100
N.A.
93.3
66.6
N.A.
73.3
26.6
N.A.
66.6
46.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
N.A.
93.3
80
N.A.
80
46.6
N.A.
66.6
53.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
23
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
89
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
67
12
0
0
0
0
0
12
34
12
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% F
% Gly:
0
0
0
0
0
0
0
0
23
0
0
100
0
0
0
% G
% His:
0
34
0
0
0
12
0
0
0
0
0
0
34
0
0
% H
% Ile:
0
0
67
0
0
0
23
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
0
12
0
0
0
0
12
0
% K
% Leu:
12
0
12
0
0
0
12
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
0
12
0
0
0
0
34
0
0
% Q
% Arg:
0
45
0
89
0
67
0
0
12
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
12
0
0
45
0
0
0
0
0
0
0
% S
% Thr:
0
12
0
0
0
0
0
12
0
0
100
0
0
78
0
% T
% Val:
0
0
23
0
0
0
67
12
12
56
0
0
0
0
0
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _