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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM53A All Species: 7.27
Human Site: S108 Identified Species: 17.78
UniProt: Q6NSI3 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NSI3 NP_001013644.1 398 42585 S108 S T V D P S E S T G S S T A P
Chimpanzee Pan troglodytes XP_001144025 398 42680 S108 S T V D P S E S T G S S T A P
Rhesus Macaque Macaca mulatta XP_001118686 341 36150 D66 S Q A A T R P D F C F L P G L
Dog Lupus familis XP_853358 334 35909 K59 P P S A P P T K R H C R S L S
Cat Felis silvestris
Mouse Mus musculus Q8BGR5 422 45921 S117 P S K R Q C R S L S F S D E M
Rat Rattus norvegicus NP_001100698 402 43038 R113 P A A P P T K R H C R S L S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509798 323 35914 P48 F E I N E E S P W R V L N G G
Chicken Gallus gallus Q5ZKN5 418 46229 S125 K R H C R S L S E P D E L A R
Frog Xenopus laevis NP_001085276 413 45804 S126 K R H C R S L S E P D E L S R
Zebra Danio Brachydanio rerio NP_001007188 379 41139 A103 S E A S P A S A A P P S K R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.9 68.8 53.7 N.A. 30.3 66.4 N.A. 35.6 53.5 50.1 32.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.7 72.1 61 N.A. 45.2 74.6 N.A. 45.7 64.3 61.2 46.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 13.3 13.3 N.A. 0 20 13.3 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 13.3 N.A. 20 33.3 N.A. 13.3 20 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 30 20 0 10 0 10 10 0 0 0 0 30 0 % A
% Cys: 0 0 0 20 0 10 0 0 0 20 10 0 0 0 0 % C
% Asp: 0 0 0 20 0 0 0 10 0 0 20 0 10 0 0 % D
% Glu: 0 20 0 0 10 10 20 0 20 0 0 20 0 10 10 % E
% Phe: 10 0 0 0 0 0 0 0 10 0 20 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 20 0 0 0 20 10 % G
% His: 0 0 20 0 0 0 0 0 10 10 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 20 0 10 0 0 0 10 10 0 0 0 0 10 0 0 % K
% Leu: 0 0 0 0 0 0 20 0 10 0 0 20 30 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 30 10 0 10 50 10 10 10 0 30 10 0 10 0 20 % P
% Gln: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 20 0 10 20 10 10 10 10 10 10 10 0 10 20 % R
% Ser: 40 10 10 10 0 40 20 50 0 10 20 50 10 20 10 % S
% Thr: 0 20 0 0 10 10 10 0 20 0 0 0 20 0 0 % T
% Val: 0 0 20 0 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _