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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM53A
All Species:
5.45
Human Site:
S135
Identified Species:
13.33
UniProt:
Q6NSI3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NSI3
NP_001013644.1
398
42585
S135
E
E
L
V
R
C
R
S
P
W
R
P
G
S
S
Chimpanzee
Pan troglodytes
XP_001144025
398
42680
S135
E
E
L
V
R
C
R
S
P
W
R
P
G
S
S
Rhesus Macaque
Macaca mulatta
XP_001118686
341
36150
V93
P
E
S
P
G
P
G
V
G
L
G
A
A
S
T
Dog
Lupus familis
XP_853358
334
35909
V86
C
S
R
V
W
T
P
V
S
K
R
W
C
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGR5
422
45921
K144
K
V
W
T
P
V
E
K
R
R
C
Y
S
G
G
Rat
Rattus norvegicus
NP_001100698
402
43038
T140
P
G
S
S
K
V
W
T
P
I
S
K
R
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509798
323
35914
F75
F
P
F
P
S
C
P
F
S
A
A
K
S
M
G
Chicken
Gallus gallus
Q5ZKN5
418
46229
R152
W
T
P
V
S
K
R
R
C
N
S
G
G
S
A
Frog
Xenopus laevis
NP_001085276
413
45804
R153
W
T
P
V
S
K
R
R
C
N
S
G
G
S
T
Zebra Danio
Brachydanio rerio
NP_001007188
379
41139
G130
R
S
S
W
R
P
Q
G
S
R
V
W
T
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
68.8
53.7
N.A.
30.3
66.4
N.A.
35.6
53.5
50.1
32.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.7
72.1
61
N.A.
45.2
74.6
N.A.
45.7
64.3
61.2
46.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
20
N.A.
0
6.6
N.A.
6.6
26.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
20
N.A.
6.6
20
N.A.
6.6
33.3
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
10
10
10
10
10
% A
% Cys:
10
0
0
0
0
30
0
0
20
0
10
0
10
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
30
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
10
0
10
10
10
0
10
20
40
10
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
20
0
10
0
10
0
20
0
0
0
% K
% Leu:
0
0
20
0
0
0
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% N
% Pro:
20
10
20
20
10
20
20
0
30
0
0
20
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
0
30
0
40
20
10
20
30
0
10
10
0
% R
% Ser:
0
20
30
10
30
0
0
20
30
0
30
0
20
50
30
% S
% Thr:
0
20
0
10
0
10
0
10
0
0
0
0
10
0
20
% T
% Val:
0
10
0
50
0
20
0
20
0
0
10
0
0
0
10
% V
% Trp:
20
0
10
10
10
0
10
0
0
20
0
20
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _