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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM45B
All Species:
13.64
Human Site:
S137
Identified Species:
30
UniProt:
Q6NSW5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NSW5
NP_996892
357
40514
S137
L
T
K
G
I
C
Q
S
E
E
N
G
S
F
L
Chimpanzee
Pan troglodytes
XP_521351
433
49072
S176
L
T
K
G
I
C
Q
S
E
E
N
G
S
F
L
Rhesus Macaque
Macaca mulatta
XP_001102570
260
29451
A61
D
F
N
P
E
K
Y
A
A
F
T
R
I
L
C
Dog
Lupus familis
XP_535029
343
39243
R137
L
S
K
D
F
D
A
R
K
A
Y
L
A
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8N2
357
40402
S137
L
T
K
G
I
C
Q
S
E
E
N
G
S
F
L
Rat
Rattus norvegicus
NP_001121153
235
26480
A35
D
G
R
K
A
Y
L
A
G
S
I
K
D
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514659
549
61761
S329
L
T
K
G
I
C
Q
S
E
E
N
G
S
F
L
Chicken
Gallus gallus
NP_001026410
216
24632
K17
L
G
V
G
L
I
E
K
D
T
N
G
D
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684048
190
21445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120151
352
40366
D141
E
N
G
T
F
V
S
D
D
F
N
S
H
C
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782995
349
39118
Q141
S
N
G
T
F
V
A
Q
D
F
D
A
K
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.5
63.3
89.6
N.A.
90.1
58.8
N.A.
53.1
52.6
N.A.
39.7
N.A.
N.A.
38.9
N.A.
51.2
Protein Similarity:
100
73.2
66.6
93
N.A.
96.3
63.3
N.A.
60.1
57.1
N.A.
47.3
N.A.
N.A.
63
N.A.
72.5
P-Site Identity:
100
100
0
13.3
N.A.
100
0
N.A.
100
33.3
N.A.
0
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
6.6
33.3
N.A.
100
20
N.A.
100
53.3
N.A.
0
N.A.
N.A.
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
19
19
10
10
0
10
10
10
10
% A
% Cys:
0
0
0
0
0
37
0
0
0
0
0
0
0
10
10
% C
% Asp:
19
0
0
10
0
10
0
10
28
0
10
0
19
0
0
% D
% Glu:
10
0
0
0
10
0
10
0
37
37
0
0
0
0
0
% E
% Phe:
0
10
0
0
28
0
0
0
0
28
0
0
0
37
10
% F
% Gly:
0
19
19
46
0
0
0
0
10
0
0
46
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
37
10
0
0
0
0
10
0
10
10
0
% I
% Lys:
0
0
46
10
0
10
0
10
10
0
0
10
10
10
0
% K
% Leu:
55
0
0
0
10
0
10
0
0
0
0
10
0
10
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
10
0
0
0
0
0
0
0
55
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
37
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% R
% Ser:
10
10
0
0
0
0
10
37
0
10
0
10
37
0
10
% S
% Thr:
0
37
0
19
0
0
0
0
0
10
10
0
0
0
0
% T
% Val:
0
0
10
0
0
19
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _