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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM45B
All Species:
9.7
Human Site:
S243
Identified Species:
21.33
UniProt:
Q6NSW5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NSW5
NP_996892
357
40514
S243
G
F
V
D
L
E
V
S
N
R
P
D
L
Y
D
Chimpanzee
Pan troglodytes
XP_521351
433
49072
S282
G
F
V
D
L
E
V
S
N
R
P
D
L
Y
D
Rhesus Macaque
Macaca mulatta
XP_001102570
260
29451
D167
A
L
V
W
H
R
Q
D
W
T
I
L
H
S
Y
Dog
Lupus familis
XP_535029
343
39243
D243
D
V
F
V
N
L
A
D
S
E
I
T
I
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8N2
357
40402
S243
G
F
V
E
L
E
V
S
N
R
P
D
L
Y
D
Rat
Rattus norvegicus
NP_001121153
235
26480
I141
L
A
D
S
E
I
I
I
A
P
L
A
K
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514659
549
61761
N435
G
F
I
D
S
E
V
N
N
R
P
D
L
Y
D
Chicken
Gallus gallus
NP_001026410
216
24632
Y123
P
V
K
M
M
E
S
Y
I
A
V
L
T
K
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684048
190
21445
W97
L
V
W
H
R
K
D
W
S
I
L
H
P
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120151
352
40366
L247
R
T
D
L
F
D
L
L
V
N
I
P
A
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782995
349
39118
F247
A
T
E
L
Y
D
L
F
V
N
L
S
T
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.5
63.3
89.6
N.A.
90.1
58.8
N.A.
53.1
52.6
N.A.
39.7
N.A.
N.A.
38.9
N.A.
51.2
Protein Similarity:
100
73.2
66.6
93
N.A.
96.3
63.3
N.A.
60.1
57.1
N.A.
47.3
N.A.
N.A.
63
N.A.
72.5
P-Site Identity:
100
100
6.6
0
N.A.
93.3
0
N.A.
80
6.6
N.A.
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
6.6
13.3
N.A.
100
6.6
N.A.
93.3
13.3
N.A.
20
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
0
0
0
10
0
10
10
0
10
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
19
28
0
19
10
19
0
0
0
37
0
10
37
% D
% Glu:
0
0
10
10
10
46
0
0
0
10
0
0
0
10
19
% E
% Phe:
0
37
10
0
10
0
0
10
0
0
0
0
0
10
0
% F
% Gly:
37
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
10
10
0
0
0
0
0
0
10
10
0
0
% H
% Ile:
0
0
10
0
0
10
10
10
10
10
28
0
10
0
0
% I
% Lys:
0
0
10
0
0
10
0
0
0
0
0
0
10
10
0
% K
% Leu:
19
10
0
19
28
10
19
10
0
0
28
19
37
0
0
% L
% Met:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
37
19
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
10
37
10
10
0
10
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
10
10
0
0
0
37
0
0
0
10
0
% R
% Ser:
0
0
0
10
10
0
10
28
19
0
0
10
0
10
0
% S
% Thr:
0
19
0
0
0
0
0
0
0
10
0
10
19
0
0
% T
% Val:
0
28
37
10
0
0
37
0
19
0
10
0
0
0
10
% V
% Trp:
0
0
10
10
0
0
0
10
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
10
0
0
0
0
0
37
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _