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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM45B
All Species:
12.42
Human Site:
Y154
Identified Species:
27.33
UniProt:
Q6NSW5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NSW5
NP_996892
357
40514
Y154
D
F
D
A
R
K
A
Y
P
A
G
S
I
K
D
Chimpanzee
Pan troglodytes
XP_521351
433
49072
Y193
D
F
D
A
R
K
A
Y
L
A
G
S
I
K
D
Rhesus Macaque
Macaca mulatta
XP_001102570
260
29451
V78
Y
L
K
H
G
S
P
V
K
M
M
E
S
Y
I
Dog
Lupus familis
XP_535029
343
39243
M154
D
I
V
S
Q
F
G
M
E
T
V
I
L
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8N2
357
40402
Y154
D
F
D
G
R
K
A
Y
L
A
G
S
I
K
D
Rat
Rattus norvegicus
NP_001121153
235
26480
L52
F
G
M
E
T
I
I
L
H
T
A
L
M
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514659
549
61761
Y346
D
F
D
A
R
K
A
Y
L
A
G
S
I
K
D
Chicken
Gallus gallus
NP_001026410
216
24632
A34
W
C
Y
P
S
V
T
A
E
L
R
T
L
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684048
190
21445
K8
M
K
H
G
S
P
V
K
M
M
E
G
Y
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120151
352
40366
I158
N
T
N
I
R
E
M
I
K
T
F
E
L
E
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782995
349
39118
I158
A
G
C
V
K
D
V
I
N
S
F
G
L
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.5
63.3
89.6
N.A.
90.1
58.8
N.A.
53.1
52.6
N.A.
39.7
N.A.
N.A.
38.9
N.A.
51.2
Protein Similarity:
100
73.2
66.6
93
N.A.
96.3
63.3
N.A.
60.1
57.1
N.A.
47.3
N.A.
N.A.
63
N.A.
72.5
P-Site Identity:
100
93.3
0
6.6
N.A.
86.6
0
N.A.
93.3
0
N.A.
0
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
93.3
0
26.6
N.A.
86.6
6.6
N.A.
93.3
13.3
N.A.
0
N.A.
N.A.
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
28
0
0
37
10
0
37
10
0
0
0
10
% A
% Cys:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
46
0
37
0
0
10
0
0
0
0
0
0
0
0
37
% D
% Glu:
0
0
0
10
0
10
0
0
19
0
10
19
0
19
0
% E
% Phe:
10
37
0
0
0
10
0
0
0
0
19
0
0
0
0
% F
% Gly:
0
19
0
19
10
0
10
0
0
0
37
19
0
0
0
% G
% His:
0
0
10
10
0
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
10
0
10
0
10
10
19
0
0
0
10
37
10
10
% I
% Lys:
0
10
10
0
10
37
0
10
19
0
0
0
0
37
10
% K
% Leu:
0
10
0
0
0
0
0
10
28
10
0
10
37
19
10
% L
% Met:
10
0
10
0
0
0
10
10
10
19
10
0
10
0
0
% M
% Asn:
10
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
10
10
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
46
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
10
19
10
0
0
0
10
0
37
10
0
0
% S
% Thr:
0
10
0
0
10
0
10
0
0
28
0
10
0
0
28
% T
% Val:
0
0
10
10
0
10
19
10
0
0
10
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
0
37
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _