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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM45B
All Species:
9.09
Human Site:
Y216
Identified Species:
20
UniProt:
Q6NSW5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NSW5
NP_996892
357
40514
Y216
D
W
T
I
L
H
S
Y
V
H
L
N
A
D
E
Chimpanzee
Pan troglodytes
XP_521351
433
49072
Y255
D
W
T
I
L
H
S
Y
V
H
L
N
A
D
E
Rhesus Macaque
Macaca mulatta
XP_001102570
260
29451
R140
T
A
L
M
L
K
K
R
I
V
V
Y
H
P
K
Dog
Lupus familis
XP_535029
343
39243
C216
E
L
E
A
L
Q
M
C
P
G
Y
I
A
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8N2
357
40402
Y216
D
W
T
I
L
H
S
Y
M
H
L
H
A
E
E
Rat
Rattus norvegicus
NP_001121153
235
26480
A114
Q
M
C
T
G
Y
I
A
G
F
V
D
L
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514659
549
61761
F408
D
W
S
V
L
H
S
F
V
H
L
H
E
E
E
Chicken
Gallus gallus
NP_001026410
216
24632
P96
L
T
A
K
D
F
N
P
E
K
Y
G
A
F
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684048
190
21445
V70
A
L
M
L
K
K
R
V
V
V
Y
H
P
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120151
352
40366
A220
D
L
I
D
D
E
L
A
E
L
K
G
Q
S
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782995
349
39118
E220
H
M
E
E
D
E
L
E
D
L
R
M
G
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.5
63.3
89.6
N.A.
90.1
58.8
N.A.
53.1
52.6
N.A.
39.7
N.A.
N.A.
38.9
N.A.
51.2
Protein Similarity:
100
73.2
66.6
93
N.A.
96.3
63.3
N.A.
60.1
57.1
N.A.
47.3
N.A.
N.A.
63
N.A.
72.5
P-Site Identity:
100
100
6.6
13.3
N.A.
80
0
N.A.
60
6.6
N.A.
6.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
33.3
20
N.A.
100
26.6
N.A.
93.3
13.3
N.A.
20
N.A.
N.A.
6.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
0
0
0
19
0
0
0
0
46
0
10
% A
% Cys:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
46
0
0
10
28
0
0
0
10
0
0
10
0
19
0
% D
% Glu:
10
0
19
10
0
19
0
10
19
0
0
0
10
28
37
% E
% Phe:
0
0
0
0
0
10
0
10
0
10
0
0
0
10
10
% F
% Gly:
0
0
0
0
10
0
0
0
10
10
0
19
10
10
0
% G
% His:
10
0
0
0
0
37
0
0
0
37
0
28
10
0
0
% H
% Ile:
0
0
10
28
0
0
10
0
10
0
0
10
0
0
10
% I
% Lys:
0
0
0
10
10
19
10
0
0
10
10
0
0
0
10
% K
% Leu:
10
28
10
10
55
0
19
0
0
19
37
0
10
0
0
% L
% Met:
0
19
10
10
0
0
10
0
10
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
19
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
10
0
0
0
10
19
0
% P
% Gln:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
0
10
0
0
10
0
% R
% Ser:
0
0
10
0
0
0
37
0
0
0
0
0
0
10
0
% S
% Thr:
10
10
28
10
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
10
0
0
0
10
37
19
19
0
0
0
10
% V
% Trp:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
28
0
0
28
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _