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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHADL All Species: 13.64
Human Site: S409 Identified Species: 33.33
UniProt: Q6NUI6 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NUI6 NP_612490.1 762 82388 S409 C V P E S R H S S C E G C G L
Chimpanzee Pan troglodytes XP_001152779 759 81976 S409 C V P E S R H S S C E G C G L
Rhesus Macaque Macaca mulatta XP_001099367 1074 115836 V642 C D N S R W H V A C R H Q N L
Dog Lupus familis XP_538355 1323 142434 S988 C A S E S R H S G C E S R G L
Cat Felis silvestris
Mouse Mus musculus O55226 358 40330 V64 L Q R N N F P V L A A N S F R
Rat Rattus norvegicus O70210 358 40385 V64 L Q R N N F P V L A A N S F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518832 723 78664 S392 C S A A S Q H S S C A G R G L
Chicken Gallus gallus XP_001232036 361 40650 L68 Q K N N F P V L P T N G F R D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663992 765 84833 S392 C E T E N R H S S C E N K G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393712 1218 136989 L457 S S M Q D L N L S G N S L D G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.6 23.6 47.1 N.A. 22 22.4 N.A. 63.9 22 N.A. 48 N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: 100 95.2 35.2 49.7 N.A. 31.1 31.1 N.A. 73.7 31.5 N.A. 63.2 N.A. N.A. 33.6 N.A. N.A.
P-Site Identity: 100 100 26.6 66.6 N.A. 0 0 N.A. 60 6.6 N.A. 60 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 100 33.3 66.6 N.A. 6.6 6.6 N.A. 66.6 6.6 N.A. 66.6 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 0 0 0 10 20 30 0 0 0 0 % A
% Cys: 60 0 0 0 0 0 0 0 0 60 0 0 20 0 0 % C
% Asp: 0 10 0 0 10 0 0 0 0 0 0 0 0 10 10 % D
% Glu: 0 10 0 40 0 0 0 0 0 0 40 0 0 0 0 % E
% Phe: 0 0 0 0 10 20 0 0 0 0 0 0 10 20 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 10 0 40 0 50 10 % G
% His: 0 0 0 0 0 0 60 0 0 0 0 10 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 20 0 0 0 0 10 0 20 20 0 0 0 10 0 50 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 20 30 30 0 10 0 0 0 20 30 0 10 0 % N
% Pro: 0 0 20 0 0 10 20 0 10 0 0 0 0 0 0 % P
% Gln: 10 20 0 10 0 10 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 20 0 10 40 0 0 0 0 10 0 20 10 20 % R
% Ser: 10 20 10 10 40 0 0 50 50 0 0 20 20 0 0 % S
% Thr: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 0 20 0 0 0 0 10 30 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _