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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHADL
All Species:
3.33
Human Site:
S736
Identified Species:
8.15
UniProt:
Q6NUI6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUI6
NP_612490.1
762
82388
S736
K
A
K
R
T
P
A
S
R
P
S
A
R
R
T
Chimpanzee
Pan troglodytes
XP_001152779
759
81976
A745
K
H
R
K
Q
L
K
A
T
T
Q
F
A
K
I
Rhesus Macaque
Macaca mulatta
XP_001099367
1074
115836
N1032
T
N
T
E
S
S
S
N
Y
H
T
G
H
Q
N
Dog
Lupus familis
XP_538355
1323
142434
A1305
F
E
M
C
P
G
W
A
A
R
K
A
K
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
O55226
358
40330
S344
R
D
T
D
A
L
R
S
C
K
S
P
T
K
R
Rat
Rattus norvegicus
O70210
358
40385
S344
R
D
T
D
A
L
R
S
C
K
S
P
T
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518832
723
78664
G707
A
I
F
E
P
C
S
G
Q
G
S
R
K
T
K
Chicken
Gallus gallus
XP_001232036
361
40650
T347
R
D
T
P
A
L
R
T
C
K
L
P
T
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663992
765
84833
K750
G
K
S
R
K
G
A
K
P
H
T
V
Q
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393712
1218
136989
A1108
V
A
D
A
V
A
E
A
A
D
S
S
R
R
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
23.6
47.1
N.A.
22
22.4
N.A.
63.9
22
N.A.
48
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
100
95.2
35.2
49.7
N.A.
31.1
31.1
N.A.
73.7
31.5
N.A.
63.2
N.A.
N.A.
33.6
N.A.
N.A.
P-Site Identity:
100
6.6
0
6.6
N.A.
13.3
13.3
N.A.
6.6
0
N.A.
20
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
100
33.3
33.3
26.6
N.A.
26.6
26.6
N.A.
26.6
20
N.A.
40
N.A.
N.A.
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
10
30
10
20
30
20
0
0
20
10
0
0
% A
% Cys:
0
0
0
10
0
10
0
0
30
0
0
0
0
0
0
% C
% Asp:
0
30
10
20
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
10
0
20
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
0
0
0
0
20
0
10
0
10
0
10
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
20
0
0
10
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
20
10
10
10
10
0
10
10
0
30
10
0
20
50
10
% K
% Leu:
0
0
0
0
0
40
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
10
20
10
0
0
10
10
0
30
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
10
0
10
20
0
% Q
% Arg:
30
0
10
20
0
0
30
0
10
10
0
10
20
20
30
% R
% Ser:
0
0
10
0
10
10
20
30
0
0
50
10
0
0
0
% S
% Thr:
10
0
40
0
10
0
0
10
10
10
20
0
30
10
30
% T
% Val:
10
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _