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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWWP2B
All Species:
5.45
Human Site:
S186
Identified Species:
12
UniProt:
Q6NUJ5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUJ5
NP_001092107.1
590
63967
S186
E
K
C
K
S
T
L
S
P
P
E
A
S
P
G
Chimpanzee
Pan troglodytes
XP_001144978
589
63912
S185
E
K
C
K
S
T
L
S
P
P
E
A
S
P
G
Rhesus Macaque
Macaca mulatta
XP_001092260
513
55832
E140
R
E
L
R
K
P
E
E
P
E
N
S
D
P
M
Dog
Lupus familis
XP_548711
398
41989
S24
H
G
A
S
Q
S
A
S
L
G
C
L
A
W
D
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z61
730
79369
E307
C
K
N
S
V
V
A
E
K
K
E
I
R
K
G
Rat
Rattus norvegicus
NP_001101977
510
54951
R137
F
P
H
P
L
W
L
R
N
T
Y
Q
Q
W
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506246
617
69027
E193
C
K
S
S
V
V
A
E
K
K
E
M
K
K
G
Chicken
Gallus gallus
XP_421830
579
64284
N173
E
K
C
K
N
T
L
N
P
E
D
E
N
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920864
597
66396
N180
E
K
C
K
N
T
L
N
S
D
E
D
S
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395213
680
75929
C222
E
R
M
E
S
T
D
C
D
S
N
P
S
M
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796495
568
61717
D171
T
A
A
S
N
R
P
D
K
N
G
L
K
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
83.5
50.5
N.A.
28.4
64
N.A.
31.2
57.4
N.A.
49
N.A.
N.A.
23.9
N.A.
22.7
Protein Similarity:
100
98.6
83.9
53.7
N.A.
45.6
69.8
N.A.
50
68.3
N.A.
63.3
N.A.
N.A.
36.7
N.A.
40.5
P-Site Identity:
100
100
13.3
6.6
N.A.
20
6.6
N.A.
20
46.6
N.A.
53.3
N.A.
N.A.
26.6
N.A.
0
P-Site Similarity:
100
100
33.3
20
N.A.
20
6.6
N.A.
20
73.3
N.A.
66.6
N.A.
N.A.
40
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
0
0
0
28
0
0
0
0
19
10
10
19
% A
% Cys:
19
0
37
0
0
0
0
10
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
10
10
10
10
10
10
0
19
% D
% Glu:
46
10
0
10
0
0
10
28
0
19
46
10
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
10
10
0
0
0
37
% G
% His:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
55
0
37
10
0
0
0
28
19
0
0
19
37
0
% K
% Leu:
0
0
10
0
10
0
46
0
10
0
0
19
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
10
0
10
10
% M
% Asn:
0
0
10
0
28
0
0
19
10
10
19
0
10
0
0
% N
% Pro:
0
10
0
10
0
10
10
0
37
19
0
10
0
28
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
10
10
0
0
% Q
% Arg:
10
10
0
10
0
10
0
10
0
0
0
0
10
0
10
% R
% Ser:
0
0
10
37
28
10
0
28
10
10
0
10
37
0
0
% S
% Thr:
10
0
0
0
0
46
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
19
19
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
19
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _