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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PWWP2B All Species: 14.85
Human Site: S382 Identified Species: 32.67
UniProt: Q6NUJ5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NUJ5 NP_001092107.1 590 63967 S382 G G L A D L S S G S S G E D D
Chimpanzee Pan troglodytes XP_001144978 589 63912 S381 G G L A D L S S G S S G E D D
Rhesus Macaque Macaca mulatta XP_001092260 513 55832 G320 D F K S C P Q G A Q G G E D L
Dog Lupus familis XP_548711 398 41989 Q204 E D F K G C P Q G P R G P E S
Cat Felis silvestris
Mouse Mus musculus Q69Z61 730 79369 S514 A G E V Q D T S R V R V P G E
Rat Rattus norvegicus NP_001101977 510 54951 S317 D R P S S G L S A S I P K L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506246 617 69027 S403 S G E V E D T S E V H V A E E
Chicken Gallus gallus XP_421830 579 64284 S371 G G L A E I S S G S S G E D D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920864 597 66396 E387 L P Q S E D A E D K N S L E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395213 680 75929 T462 T C L E P G S T E N Q Q N W N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796495 568 61717 V356 K L V G N V T V K P I T L L N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 83.5 50.5 N.A. 28.4 64 N.A. 31.2 57.4 N.A. 49 N.A. N.A. 23.9 N.A. 22.7
Protein Similarity: 100 98.6 83.9 53.7 N.A. 45.6 69.8 N.A. 50 68.3 N.A. 63.3 N.A. N.A. 36.7 N.A. 40.5
P-Site Identity: 100 100 20 13.3 N.A. 13.3 13.3 N.A. 13.3 86.6 N.A. 0 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 100 26.6 20 N.A. 26.6 26.6 N.A. 40 100 N.A. 33.3 N.A. N.A. 33.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 28 0 0 10 0 19 0 0 0 10 0 0 % A
% Cys: 0 10 0 0 10 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 10 0 0 19 28 0 0 10 0 0 0 0 37 28 % D
% Glu: 10 0 19 10 28 0 0 10 19 0 0 0 37 28 19 % E
% Phe: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 28 46 0 10 10 19 0 10 37 0 10 46 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 19 0 0 0 0 % I
% Lys: 10 0 10 10 0 0 0 0 10 10 0 0 10 0 10 % K
% Leu: 10 10 37 0 0 19 10 0 0 0 0 0 19 19 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 10 10 0 10 0 19 % N
% Pro: 0 10 10 0 10 10 10 0 0 19 0 10 19 0 0 % P
% Gln: 0 0 10 0 10 0 10 10 0 10 10 10 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 10 0 19 0 0 0 0 % R
% Ser: 10 0 0 28 10 0 37 55 0 37 28 10 0 0 10 % S
% Thr: 10 0 0 0 0 0 28 10 0 0 0 10 0 0 0 % T
% Val: 0 0 10 19 0 10 0 10 0 19 0 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _