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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWWP2B
All Species:
17.58
Human Site:
S421
Identified Species:
38.67
UniProt:
Q6NUJ5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUJ5
NP_001092107.1
590
63967
S421
R
A
D
C
A
S
E
S
A
C
S
S
D
S
L
Chimpanzee
Pan troglodytes
XP_001144978
589
63912
S420
R
A
D
C
A
S
E
S
A
C
S
S
D
S
L
Rhesus Macaque
Macaca mulatta
XP_001092260
513
55832
G358
L
D
E
A
R
S
S
G
S
E
G
T
P
A
D
Dog
Lupus familis
XP_548711
398
41989
S242
S
L
D
E
S
K
S
S
S
S
E
V
T
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z61
730
79369
S554
T
S
D
S
S
S
A
S
V
C
S
I
D
S
M
Rat
Rattus norvegicus
NP_001101977
510
54951
L355
G
N
G
E
H
E
P
L
Y
R
A
E
L
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506246
617
69027
D448
S
A
S
V
C
S
V
D
S
T
D
D
L
K
S
Chicken
Gallus gallus
XP_421830
579
64284
S410
K
A
D
S
S
S
L
S
V
C
S
N
D
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920864
597
66396
S426
K
A
D
S
S
S
L
S
V
C
S
S
D
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395213
680
75929
Y501
K
R
L
N
T
N
A
Y
A
R
C
D
Y
P
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796495
568
61717
C394
I
S
D
T
A
S
D
C
S
S
Y
T
S
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
83.5
50.5
N.A.
28.4
64
N.A.
31.2
57.4
N.A.
49
N.A.
N.A.
23.9
N.A.
22.7
Protein Similarity:
100
98.6
83.9
53.7
N.A.
45.6
69.8
N.A.
50
68.3
N.A.
63.3
N.A.
N.A.
36.7
N.A.
40.5
P-Site Identity:
100
100
6.6
20
N.A.
46.6
0
N.A.
13.3
60
N.A.
66.6
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
100
33.3
33.3
N.A.
66.6
6.6
N.A.
20
80
N.A.
80
N.A.
N.A.
26.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
0
10
28
0
19
0
28
0
10
0
0
10
0
% A
% Cys:
0
0
0
19
10
0
0
10
0
46
10
0
0
0
0
% C
% Asp:
0
10
64
0
0
0
10
10
0
0
10
19
46
0
10
% D
% Glu:
0
0
10
19
0
10
19
0
0
10
10
10
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
0
0
10
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
28
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
10
10
0
0
0
19
10
0
0
0
0
19
0
37
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
10
0
10
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
10
0
0
10
0
0
0
0
19
0
0
0
10
0
% R
% Ser:
19
19
10
28
37
73
19
55
37
19
46
28
10
55
10
% S
% Thr:
10
0
0
10
10
0
0
0
0
10
0
19
10
0
0
% T
% Val:
0
0
0
10
0
0
10
0
28
0
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
10
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _