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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWWP2B
All Species:
4.55
Human Site:
S43
Identified Species:
10
UniProt:
Q6NUJ5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUJ5
NP_001092107.1
590
63967
S43
L
L
D
C
T
K
K
S
G
L
F
G
L
P
P
Chimpanzee
Pan troglodytes
XP_001144978
589
63912
S43
L
L
D
C
T
K
K
S
G
L
F
G
L
P
P
Rhesus Macaque
Macaca mulatta
XP_001092260
513
55832
Dog
Lupus familis
XP_548711
398
41989
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z61
730
79369
A59
E
A
D
G
R
Q
S
A
P
Q
A
D
E
Q
P
Rat
Rattus norvegicus
NP_001101977
510
54951
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506246
617
69027
K30
L
H
L
L
P
E
S
K
I
Q
V
T
L
N
L
Chicken
Gallus gallus
XP_421830
579
64284
Q27
E
S
S
A
L
A
A
Q
P
S
R
G
A
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920864
597
66396
E34
V
V
T
L
R
Y
R
E
K
S
F
T
G
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395213
680
75929
K41
K
S
T
L
T
A
A
K
V
D
L
R
R
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796495
568
61717
L27
V
E
Q
A
L
P
D
L
L
M
V
S
L
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
83.5
50.5
N.A.
28.4
64
N.A.
31.2
57.4
N.A.
49
N.A.
N.A.
23.9
N.A.
22.7
Protein Similarity:
100
98.6
83.9
53.7
N.A.
45.6
69.8
N.A.
50
68.3
N.A.
63.3
N.A.
N.A.
36.7
N.A.
40.5
P-Site Identity:
100
100
0
0
N.A.
13.3
0
N.A.
13.3
13.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
0
0
N.A.
26.6
0
N.A.
20
13.3
N.A.
26.6
N.A.
N.A.
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
19
0
19
19
10
0
0
10
0
10
0
0
% A
% Cys:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
28
0
0
0
10
0
0
10
0
10
0
0
0
% D
% Glu:
19
10
0
0
0
10
0
10
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
28
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
19
0
0
28
10
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
10
% I
% Lys:
10
0
0
0
0
19
19
19
10
0
0
0
0
10
0
% K
% Leu:
28
19
10
28
19
0
0
10
10
19
10
0
37
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% N
% Pro:
0
0
0
0
10
10
0
0
19
0
0
0
0
28
28
% P
% Gln:
0
0
10
0
0
10
0
10
0
19
0
0
0
10
0
% Q
% Arg:
0
0
0
0
19
0
10
0
0
0
10
10
10
0
0
% R
% Ser:
0
19
10
0
0
0
19
19
0
19
0
10
0
0
19
% S
% Thr:
0
0
19
0
28
0
0
0
0
0
0
19
0
0
0
% T
% Val:
19
10
0
0
0
0
0
0
10
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _