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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWWP2B
All Species:
13.64
Human Site:
S476
Identified Species:
30
UniProt:
Q6NUJ5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUJ5
NP_001092107.1
590
63967
S476
T
V
R
L
H
T
Q
S
V
S
E
C
I
T
E
Chimpanzee
Pan troglodytes
XP_001144978
589
63912
S475
T
V
R
L
H
T
Q
S
V
S
E
C
I
T
E
Rhesus Macaque
Macaca mulatta
XP_001092260
513
55832
V413
E
D
G
R
T
V
A
V
G
D
I
V
W
G
K
Dog
Lupus familis
XP_548711
398
41989
A297
T
E
D
G
R
T
V
A
V
G
D
I
V
W
G
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z61
730
79369
K609
N
S
L
R
N
S
L
K
M
K
I
F
S
K
N
Rat
Rattus norvegicus
NP_001101977
510
54951
G410
R
F
P
Q
G
K
H
G
R
D
G
L
A
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506246
617
69027
N503
K
M
K
V
F
S
K
N
V
S
K
C
V
T
P
Chicken
Gallus gallus
XP_421830
579
64284
S465
T
V
R
L
H
T
Q
S
V
S
K
C
V
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920864
597
66396
S481
T
V
R
L
H
T
R
S
M
S
K
C
V
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395213
680
75929
P556
M
M
R
L
A
A
T
P
V
E
H
C
L
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796495
568
61717
N449
K
P
S
N
H
K
K
N
V
T
K
S
I
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
83.5
50.5
N.A.
28.4
64
N.A.
31.2
57.4
N.A.
49
N.A.
N.A.
23.9
N.A.
22.7
Protein Similarity:
100
98.6
83.9
53.7
N.A.
45.6
69.8
N.A.
50
68.3
N.A.
63.3
N.A.
N.A.
36.7
N.A.
40.5
P-Site Identity:
100
100
0
20
N.A.
0
0
N.A.
26.6
86.6
N.A.
73.3
N.A.
N.A.
33.3
N.A.
20
P-Site Similarity:
100
100
6.6
40
N.A.
20
0
N.A.
80
100
N.A.
100
N.A.
N.A.
46.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
10
10
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
19
10
0
0
0
0
% D
% Glu:
10
10
0
0
0
0
0
0
0
10
19
0
0
0
37
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
0
0
10
10
10
0
0
10
10
10
10
0
0
10
10
% G
% His:
0
0
0
0
46
0
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
19
10
28
0
0
% I
% Lys:
19
0
10
0
0
19
19
10
0
10
37
0
0
10
10
% K
% Leu:
0
0
10
46
0
0
10
0
0
0
0
10
10
10
10
% L
% Met:
10
19
0
0
0
0
0
0
19
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
10
0
0
19
0
0
0
0
0
0
10
% N
% Pro:
0
10
10
0
0
0
0
10
0
0
0
0
0
0
19
% P
% Gln:
0
0
0
10
0
0
28
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
46
19
10
0
10
0
10
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
0
19
0
37
0
46
0
10
10
0
0
% S
% Thr:
46
0
0
0
10
46
10
0
0
10
0
0
0
55
0
% T
% Val:
0
37
0
10
0
10
10
10
64
0
0
10
37
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _