KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWWP2B
All Species:
14.85
Human Site:
S522
Identified Species:
32.67
UniProt:
Q6NUJ5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUJ5
NP_001092107.1
590
63967
S522
Q
K
E
D
G
E
P
S
W
R
E
A
K
V
S
Chimpanzee
Pan troglodytes
XP_001144978
589
63912
S521
Q
K
E
D
G
E
P
S
W
R
E
A
K
V
S
Rhesus Macaque
Macaca mulatta
XP_001092260
513
55832
A449
G
E
P
S
W
R
E
A
K
V
S
W
F
G
S
Dog
Lupus familis
XP_548711
398
41989
E333
D
G
E
P
S
W
Q
E
A
K
V
S
W
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z61
730
79369
A662
R
K
D
N
G
L
L
A
R
Q
E
A
R
I
S
Rat
Rattus norvegicus
NP_001101977
510
54951
G446
L
D
E
L
K
S
S
G
S
E
V
T
S
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506246
617
69027
V549
R
K
D
N
G
L
L
V
R
Q
E
A
R
I
S
Chicken
Gallus gallus
XP_421830
579
64284
S511
Q
K
E
N
G
E
P
S
W
R
E
A
K
V
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920864
597
66396
P529
E
D
G
E
V
D
A
P
W
P
E
A
K
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395213
680
75929
S602
C
K
E
D
G
T
S
S
G
P
Q
A
H
V
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796495
568
61717
T495
R
S
N
E
G
G
I
T
L
Q
E
A
Q
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
83.5
50.5
N.A.
28.4
64
N.A.
31.2
57.4
N.A.
49
N.A.
N.A.
23.9
N.A.
22.7
Protein Similarity:
100
98.6
83.9
53.7
N.A.
45.6
69.8
N.A.
50
68.3
N.A.
63.3
N.A.
N.A.
36.7
N.A.
40.5
P-Site Identity:
100
100
6.6
6.6
N.A.
33.3
6.6
N.A.
33.3
93.3
N.A.
40
N.A.
N.A.
46.6
N.A.
20
P-Site Similarity:
100
100
20
20
N.A.
80
6.6
N.A.
73.3
100
N.A.
60
N.A.
N.A.
60
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
19
10
0
0
73
0
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
19
28
0
10
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
10
55
19
0
28
10
10
0
10
64
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% F
% Gly:
10
10
10
0
64
10
0
10
10
0
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
28
0
% I
% Lys:
0
55
0
0
10
0
0
0
10
10
0
0
37
0
0
% K
% Leu:
10
0
0
10
0
19
19
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
28
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
0
0
28
10
0
19
0
0
0
10
0
% P
% Gln:
28
0
0
0
0
0
10
0
0
28
10
0
10
0
0
% Q
% Arg:
28
0
0
0
0
10
0
0
19
28
0
0
19
0
0
% R
% Ser:
0
10
0
10
10
10
19
37
10
0
10
10
10
0
64
% S
% Thr:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
10
% T
% Val:
0
0
0
0
10
0
0
10
0
10
19
0
0
46
0
% V
% Trp:
0
0
0
0
10
10
0
0
37
0
0
10
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _