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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PWWP2B All Species: 8.79
Human Site: T151 Identified Species: 19.33
UniProt: Q6NUJ5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NUJ5 NP_001092107.1 590 63967 T151 P P R T I K R T R R R L S R N
Chimpanzee Pan troglodytes XP_001144978 589 63912 T150 P P R T I K R T R R R L S R N
Rhesus Macaque Macaca mulatta XP_001092260 513 55832 K105 Q V L C E K C K S T L S P P E
Dog Lupus familis XP_548711 398 41989
Cat Felis silvestris
Mouse Mus musculus Q69Z61 730 79369 P272 P P R K I K R P K R K M Y R E
Rat Rattus norvegicus NP_001101977 510 54951 V102 D Q P P K T A V P E P P P P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506246 617 69027 P158 P P R K I K R P K R K M Y R E
Chicken Gallus gallus XP_421830 579 64284 T138 P P R A I K R T R R R L S R N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920864 597 66396 I145 P Q P P P R P I K R K K R R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395213 680 75929 E187 N N A L Q A N E K V K I S P S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796495 568 61717 V136 K P K T I S H V R S R Q F R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 83.5 50.5 N.A. 28.4 64 N.A. 31.2 57.4 N.A. 49 N.A. N.A. 23.9 N.A. 22.7
Protein Similarity: 100 98.6 83.9 53.7 N.A. 45.6 69.8 N.A. 50 68.3 N.A. 63.3 N.A. N.A. 36.7 N.A. 40.5
P-Site Identity: 100 100 6.6 0 N.A. 53.3 0 N.A. 53.3 93.3 N.A. 20 N.A. N.A. 6.6 N.A. 40
P-Site Similarity: 100 100 6.6 0 N.A. 73.3 0 N.A. 73.3 93.3 N.A. 46.6 N.A. N.A. 33.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 10 10 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 10 0 10 0 0 0 0 28 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 55 0 0 10 0 0 0 10 0 0 0 % I
% Lys: 10 0 10 19 10 55 0 10 37 0 37 10 0 0 0 % K
% Leu: 0 0 10 10 0 0 0 0 0 0 10 28 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % M
% Asn: 10 10 0 0 0 0 10 0 0 0 0 0 0 0 28 % N
% Pro: 55 55 19 19 10 0 10 19 10 0 10 10 19 28 0 % P
% Gln: 10 19 0 0 10 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 46 0 0 10 46 0 37 55 37 0 10 64 0 % R
% Ser: 0 0 0 0 0 10 0 0 10 10 0 10 37 0 19 % S
% Thr: 0 0 0 28 0 10 0 28 0 10 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 19 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _