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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PWWP2B All Species: 4.24
Human Site: T96 Identified Species: 9.33
UniProt: Q6NUJ5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NUJ5 NP_001092107.1 590 63967 T96 R G V Q P P E T T R P E P P P
Chimpanzee Pan troglodytes XP_001144978 589 63912 T96 R G V Q P E T T G P E P P P P
Rhesus Macaque Macaca mulatta XP_001092260 513 55832 H51 F E G A P F P H P L W L R D T
Dog Lupus familis XP_548711 398 41989
Cat Felis silvestris
Mouse Mus musculus Q69Z61 730 79369 A114 A P E Q P E D A P R P P P A P
Rat Rattus norvegicus NP_001101977 510 54951 L48 K K S G L F G L S P S T L L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506246 617 69027 E93 K S F Q E G T E I K C E V N G
Chicken Gallus gallus XP_421830 579 64284 E80 A R D P T P G E T Q P Q P G D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920864 597 66396 D91 Q P T Q R P K D E N T E P E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395213 680 75929 K126 R C G Q Q P Q K A S R V L F S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796495 568 61717 T76 F G V P V I D T A F I K H E Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 83.5 50.5 N.A. 28.4 64 N.A. 31.2 57.4 N.A. 49 N.A. N.A. 23.9 N.A. 22.7
Protein Similarity: 100 98.6 83.9 53.7 N.A. 45.6 69.8 N.A. 50 68.3 N.A. 63.3 N.A. N.A. 36.7 N.A. 40.5
P-Site Identity: 100 60 6.6 0 N.A. 40 6.6 N.A. 13.3 26.6 N.A. 26.6 N.A. N.A. 20 N.A. 20
P-Site Similarity: 100 60 6.6 0 N.A. 46.6 20 N.A. 26.6 40 N.A. 40 N.A. N.A. 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 10 0 0 0 10 19 0 0 0 0 10 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 19 10 0 0 0 0 0 10 10 % D
% Glu: 0 10 10 0 10 19 10 19 10 0 10 28 0 19 10 % E
% Phe: 19 0 10 0 0 19 0 0 0 10 0 0 0 10 0 % F
% Gly: 0 28 19 10 0 10 19 0 10 0 0 0 0 10 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 10 0 10 0 0 0 0 % I
% Lys: 19 10 0 0 0 0 10 10 0 10 0 10 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 10 0 10 0 10 19 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % N
% Pro: 0 19 0 19 37 37 10 0 19 19 28 19 46 19 37 % P
% Gln: 10 0 0 55 10 0 10 0 0 10 0 10 0 0 10 % Q
% Arg: 28 10 0 0 10 0 0 0 0 19 10 0 10 0 0 % R
% Ser: 0 10 10 0 0 0 0 0 10 10 10 0 0 0 10 % S
% Thr: 0 0 10 0 10 0 19 28 19 0 10 10 0 0 10 % T
% Val: 0 0 28 0 10 0 0 0 0 0 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _