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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PWWP2B
All Species:
17.58
Human Site:
Y136
Identified Species:
38.67
UniProt:
Q6NUJ5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUJ5
NP_001092107.1
590
63967
Y136
P
L
W
L
R
D
T
Y
K
L
W
V
P
Q
P
Chimpanzee
Pan troglodytes
XP_001144978
589
63912
Y135
P
L
W
L
R
D
T
Y
K
L
W
V
P
Q
P
Rhesus Macaque
Macaca mulatta
XP_001092260
513
55832
S90
D
P
G
R
L
I
L
S
T
I
R
L
R
P
R
Dog
Lupus familis
XP_548711
398
41989
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z61
730
79369
Y257
P
L
F
I
R
D
T
Y
N
Q
S
I
P
Q
P
Rat
Rattus norvegicus
NP_001101977
510
54951
P87
L
E
T
G
P
L
P
P
H
H
Q
D
P
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506246
617
69027
Y143
P
L
F
I
R
D
T
Y
N
Q
S
I
P
Q
P
Chicken
Gallus gallus
XP_421830
579
64284
Y123
P
L
W
L
R
H
T
Y
S
Q
W
V
P
Q
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920864
597
66396
R130
F
P
Q
P
I
W
V
R
H
T
Y
N
Q
W
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395213
680
75929
S172
P
S
L
I
P
K
I
S
R
L
Q
P
N
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796495
568
61717
K121
A
R
P
L
L
F
G
K
K
E
K
T
P
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
83.5
50.5
N.A.
28.4
64
N.A.
31.2
57.4
N.A.
49
N.A.
N.A.
23.9
N.A.
22.7
Protein Similarity:
100
98.6
83.9
53.7
N.A.
45.6
69.8
N.A.
50
68.3
N.A.
63.3
N.A.
N.A.
36.7
N.A.
40.5
P-Site Identity:
100
100
0
0
N.A.
60
6.6
N.A.
60
80
N.A.
0
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
100
100
13.3
0
N.A.
80
13.3
N.A.
80
80
N.A.
6.6
N.A.
N.A.
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
37
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
10
0
0
0
28
0
% E
% Phe:
10
0
19
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
19
10
0
0
0
0
0
% H
% Ile:
0
0
0
28
10
10
10
0
0
10
0
19
0
0
19
% I
% Lys:
0
0
0
0
0
10
0
10
28
0
10
0
0
0
10
% K
% Leu:
10
46
10
37
19
10
10
0
0
28
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
19
0
0
10
10
0
0
% N
% Pro:
55
19
10
10
19
0
10
10
0
0
0
10
64
10
46
% P
% Gln:
0
0
10
0
0
0
0
0
0
28
19
0
10
46
0
% Q
% Arg:
0
10
0
10
46
0
0
10
10
0
10
0
10
0
10
% R
% Ser:
0
10
0
0
0
0
0
19
10
0
19
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
46
0
10
10
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
28
0
0
10
% V
% Trp:
0
0
28
0
0
10
0
0
0
0
28
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
46
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _