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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP3
All Species:
37.88
Human Site:
S152
Identified Species:
75.76
UniProt:
Q6NUK4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUK4
NP_001001330.1
255
29264
S152
T
E
R
L
R
S
F
S
M
H
D
L
T
T
I
Chimpanzee
Pan troglodytes
XP_001162084
294
33660
S191
T
E
R
L
R
S
F
S
M
H
D
L
T
T
I
Rhesus Macaque
Macaca mulatta
XP_001090368
255
29158
S152
T
E
R
L
R
S
F
S
M
H
D
L
T
A
I
Dog
Lupus familis
XP_536364
274
31676
S171
T
E
R
L
R
S
F
S
M
H
D
L
T
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99KK1
254
29195
S152
T
E
R
L
R
S
F
S
M
H
D
L
T
A
I
Rat
Rattus norvegicus
Q4QQW1
257
29642
S152
A
G
R
L
R
S
F
S
M
Q
D
L
R
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510875
359
41305
S256
T
E
R
L
R
S
F
S
M
H
D
L
T
A
I
Chicken
Gallus gallus
XP_421536
431
48387
S328
T
E
K
L
R
S
F
S
M
H
D
L
T
T
I
Frog
Xenopus laevis
NP_001083678
263
30121
S152
T
E
R
L
R
S
F
S
M
H
D
L
T
A
V
Zebra Danio
Brachydanio rerio
Q7ZVX5
256
29204
S152
T
E
K
L
R
S
F
S
M
H
D
L
T
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10010
229
26592
V127
R
I
G
S
K
S
L
V
Y
A
K
D
V
V
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LEM6
315
35085
E154
T
P
K
P
K
P
K
E
K
K
Q
A
A
A
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
98
84.3
N.A.
92.1
52.9
N.A.
62.4
49.6
72.6
69.5
N.A.
N.A.
N.A.
34.9
N.A.
Protein Similarity:
100
86
99.2
87.2
N.A.
95.2
67.3
N.A.
65.1
54.7
85.1
82
N.A.
N.A.
N.A.
55.6
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
66.6
N.A.
93.3
93.3
86.6
86.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
73.3
N.A.
93.3
100
93.3
93.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
9
0
9
9
50
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
84
9
0
0
0
% D
% Glu:
0
75
0
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
84
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
75
% I
% Lys:
0
0
25
0
17
0
9
0
9
9
9
0
0
0
0
% K
% Leu:
0
0
0
84
0
0
9
0
0
0
0
84
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
84
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
9
0
9
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
9
0
0
9
0
% Q
% Arg:
9
0
67
0
84
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
0
0
9
0
92
0
84
0
0
0
0
0
9
0
% S
% Thr:
84
0
0
0
0
0
0
0
0
0
0
0
75
25
0
% T
% Val:
0
0
0
0
0
0
0
9
0
0
0
0
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _