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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP3
All Species:
10.91
Human Site:
S185
Identified Species:
21.82
UniProt:
Q6NUK4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUK4
NP_001001330.1
255
29264
S185
K
K
S
K
P
A
P
S
E
S
A
G
Y
G
I
Chimpanzee
Pan troglodytes
XP_001162084
294
33660
S224
K
K
S
K
P
A
P
S
E
S
A
G
Y
G
I
Rhesus Macaque
Macaca mulatta
XP_001090368
255
29158
G185
K
K
S
K
P
A
P
G
E
S
A
G
Y
G
I
Dog
Lupus familis
XP_536364
274
31676
G204
K
K
S
K
S
V
S
G
E
S
A
G
Y
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99KK1
254
29195
E185
R
K
G
K
Q
A
T
E
S
P
A
Y
G
I
P
Rat
Rattus norvegicus
Q4QQW1
257
29642
G185
P
R
R
R
P
P
I
G
Y
R
P
G
G
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510875
359
41305
S289
K
K
A
K
A
S
T
S
E
S
V
G
I
A
T
Chicken
Gallus gallus
XP_421536
431
48387
N361
K
K
T
R
A
S
A
N
E
S
A
G
F
P
L
Frog
Xenopus laevis
NP_001083678
263
30121
S185
K
K
A
R
A
S
V
S
D
S
S
G
F
G
S
Zebra Danio
Brachydanio rerio
Q7ZVX5
256
29204
E185
M
D
Q
P
D
G
A
E
Y
Y
H
G
D
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10010
229
26592
E160
S
A
N
D
V
G
S
E
R
E
A
L
T
K
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LEM6
315
35085
Q187
S
N
P
Q
V
R
L
Q
S
K
K
P
Q
L
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
98
84.3
N.A.
92.1
52.9
N.A.
62.4
49.6
72.6
69.5
N.A.
N.A.
N.A.
34.9
N.A.
Protein Similarity:
100
86
99.2
87.2
N.A.
95.2
67.3
N.A.
65.1
54.7
85.1
82
N.A.
N.A.
N.A.
55.6
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
26.6
13.3
N.A.
46.6
40
40
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
73.3
N.A.
33.3
26.6
N.A.
60
80
80
6.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
0
25
34
17
0
0
0
59
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
9
0
0
0
9
0
0
0
9
9
9
% D
% Glu:
0
0
0
0
0
0
0
25
50
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% F
% Gly:
0
0
9
0
0
17
0
25
0
0
0
75
17
42
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
9
9
34
% I
% Lys:
59
67
0
50
0
0
0
0
0
9
9
0
0
9
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
0
0
9
0
17
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
0
9
0
0
0
0
0
0
9
% N
% Pro:
9
0
9
9
34
9
25
0
0
9
9
9
0
9
9
% P
% Gln:
0
0
9
9
9
0
0
9
0
0
0
0
9
0
9
% Q
% Arg:
9
9
9
25
0
9
0
0
9
9
0
0
0
0
0
% R
% Ser:
17
0
34
0
9
25
17
34
17
59
9
0
0
0
9
% S
% Thr:
0
0
9
0
0
0
17
0
0
0
0
0
9
0
9
% T
% Val:
0
0
0
0
17
9
9
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
17
9
0
9
34
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _