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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP3
All Species:
30.91
Human Site:
S225
Identified Species:
61.82
UniProt:
Q6NUK4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUK4
NP_001001330.1
255
29264
S225
K
G
L
R
R
S
Q
S
M
K
S
V
K
T
T
Chimpanzee
Pan troglodytes
XP_001162084
294
33660
S264
K
G
L
R
R
S
Q
S
M
K
S
V
K
T
T
Rhesus Macaque
Macaca mulatta
XP_001090368
255
29158
S225
K
G
L
R
R
S
Q
S
M
K
S
V
K
T
T
Dog
Lupus familis
XP_536364
274
31676
S244
R
G
L
R
R
S
Q
S
M
K
S
V
K
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99KK1
254
29195
M225
A
L
R
R
S
Q
S
M
K
S
V
K
T
I
K
Rat
Rattus norvegicus
Q4QQW1
257
29642
L225
P
L
S
R
S
Q
S
L
R
V
V
K
R
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510875
359
41305
S329
R
G
L
R
R
S
Q
S
M
K
S
V
K
T
I
Chicken
Gallus gallus
XP_421536
431
48387
S401
R
G
L
R
R
T
Q
S
M
K
S
V
K
T
V
Frog
Xenopus laevis
NP_001083678
263
30121
S225
K
G
L
R
R
S
Q
S
M
R
S
V
K
V
I
Zebra Danio
Brachydanio rerio
Q7ZVX5
256
29204
S225
Q
S
V
K
V
T
R
S
K
L
R
R
D
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10010
229
26592
S200
R
A
S
S
R
S
R
S
R
S
R
T
I
D
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LEM6
315
35085
T227
A
K
A
S
V
S
Q
T
K
L
T
T
L
T
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
98
84.3
N.A.
92.1
52.9
N.A.
62.4
49.6
72.6
69.5
N.A.
N.A.
N.A.
34.9
N.A.
Protein Similarity:
100
86
99.2
87.2
N.A.
95.2
67.3
N.A.
65.1
54.7
85.1
82
N.A.
N.A.
N.A.
55.6
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
6.6
6.6
N.A.
86.6
80
80
6.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
6.6
13.3
N.A.
93.3
93.3
86.6
40
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
9
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
17
% I
% Lys:
34
9
0
9
0
0
0
0
25
50
0
17
59
9
9
% K
% Leu:
0
17
59
0
0
0
0
9
0
17
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
9
59
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
9
0
0
0
0
17
67
0
0
0
0
0
0
0
0
% Q
% Arg:
34
0
9
75
67
0
17
0
17
9
17
9
9
0
9
% R
% Ser:
0
9
17
17
17
67
17
75
0
17
59
0
0
0
9
% S
% Thr:
0
0
0
0
0
17
0
9
0
0
9
17
9
59
25
% T
% Val:
0
0
9
0
17
0
0
0
0
9
17
59
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _