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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP3
All Species:
40.3
Human Site:
T117
Identified Species:
80.61
UniProt:
Q6NUK4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUK4
NP_001001330.1
255
29264
T117
A
K
E
R
G
Y
E
T
M
V
N
F
G
R
Q
Chimpanzee
Pan troglodytes
XP_001162084
294
33660
T156
A
K
E
R
G
Y
E
T
M
V
N
F
G
R
Q
Rhesus Macaque
Macaca mulatta
XP_001090368
255
29158
T117
A
K
E
R
G
Y
E
T
M
V
N
F
G
R
Q
Dog
Lupus familis
XP_536364
274
31676
T136
A
K
E
R
G
Y
E
T
V
V
N
F
G
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99KK1
254
29195
T117
A
K
E
R
G
Y
E
T
M
V
N
F
G
R
Q
Rat
Rattus norvegicus
Q4QQW1
257
29642
T117
A
K
E
R
S
Y
E
T
M
L
S
F
G
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510875
359
41305
T221
A
K
E
R
G
Y
E
T
M
V
N
F
G
R
Q
Chicken
Gallus gallus
XP_421536
431
48387
T293
A
K
E
R
G
Y
E
T
M
V
N
F
G
R
Q
Frog
Xenopus laevis
NP_001083678
263
30121
T117
A
K
E
K
G
Y
E
T
M
V
H
F
G
K
Q
Zebra Danio
Brachydanio rerio
Q7ZVX5
256
29204
T117
A
K
E
R
S
Y
E
T
M
V
N
F
G
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10010
229
26592
V92
S
I
L
Y
R
K
W
V
H
P
T
L
N
R
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LEM6
315
35085
L119
L
R
T
K
A
G
D
L
A
V
I
Y
C
R
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
98
84.3
N.A.
92.1
52.9
N.A.
62.4
49.6
72.6
69.5
N.A.
N.A.
N.A.
34.9
N.A.
Protein Similarity:
100
86
99.2
87.2
N.A.
95.2
67.3
N.A.
65.1
54.7
85.1
82
N.A.
N.A.
N.A.
55.6
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
66.6
N.A.
100
100
80
86.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
100
100
93.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
84
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
84
0
0
0
84
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
84
0
0
0
% F
% Gly:
0
0
0
0
67
9
0
0
0
0
0
0
84
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
9
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
84
0
17
0
9
0
0
0
0
0
0
0
25
9
% K
% Leu:
9
0
9
0
0
0
0
9
0
9
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
67
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% Q
% Arg:
0
9
0
75
9
0
0
0
0
0
0
0
0
75
9
% R
% Ser:
9
0
0
0
17
0
0
0
0
0
9
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
84
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
9
9
84
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
84
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _