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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP3
All Species:
40.61
Human Site:
T29
Identified Species:
81.21
UniProt:
Q6NUK4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUK4
NP_001001330.1
255
29264
T29
Y
S
Y
K
A
V
K
T
K
N
V
K
E
Y
V
Chimpanzee
Pan troglodytes
XP_001162084
294
33660
T68
Y
S
Y
K
A
V
K
T
K
N
V
K
E
Y
V
Rhesus Macaque
Macaca mulatta
XP_001090368
255
29158
T29
Y
S
Y
K
A
V
K
T
K
N
V
K
E
Y
V
Dog
Lupus familis
XP_536364
274
31676
T48
Y
S
Y
K
A
V
K
T
K
N
V
K
E
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99KK1
254
29195
T29
Y
S
Y
K
A
V
K
T
K
N
V
K
E
Y
V
Rat
Rattus norvegicus
Q4QQW1
257
29642
S29
A
S
Y
K
A
V
K
S
K
N
I
R
E
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510875
359
41305
T133
Y
S
Y
K
A
V
K
T
K
N
V
K
E
Y
V
Chicken
Gallus gallus
XP_421536
431
48387
T205
Y
S
Y
K
A
V
K
T
K
N
V
K
E
Y
V
Frog
Xenopus laevis
NP_001083678
263
30121
T29
F
S
Y
K
A
V
R
T
K
N
V
K
E
Y
V
Zebra Danio
Brachydanio rerio
Q7ZVX5
256
29204
T29
Y
S
Y
K
A
V
K
T
K
N
V
K
E
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10010
229
26592
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LEM6
315
35085
K31
Y
K
A
V
E
K
N
K
P
E
M
Q
Q
L
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
98
84.3
N.A.
92.1
52.9
N.A.
62.4
49.6
72.6
69.5
N.A.
N.A.
N.A.
34.9
N.A.
Protein Similarity:
100
86
99.2
87.2
N.A.
95.2
67.3
N.A.
65.1
54.7
85.1
82
N.A.
N.A.
N.A.
55.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
73.3
N.A.
100
100
86.6
100
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
100
100
100
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
84
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
9
0
0
84
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
9
0
84
0
9
75
9
84
0
0
75
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
84
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
9
% R
% Ser:
0
84
0
0
0
0
0
9
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
84
0
0
0
0
75
0
0
0
84
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
75
0
84
0
0
0
0
0
0
0
0
0
0
84
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _