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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1B
All Species:
8.48
Human Site:
S261
Identified Species:
16.97
UniProt:
Q6NUM6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUM6
NP_001138912.1
668
76946
S261
F
G
G
E
D
H
Q
S
L
N
S
I
V
D
V
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
S324
F
G
G
E
D
R
Q
S
L
N
S
I
V
D
V
Dog
Lupus familis
XP_536836
714
81505
E312
C
V
K
K
E
K
R
E
K
E
E
Q
E
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
S299
Q
D
Y
Q
S
L
T
S
V
V
D
V
E
D
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
S316
E
E
A
G
G
T
D
S
V
V
D
V
E
D
L
Frog
Xenopus laevis
Q2KHP8
735
84095
G311
P
E
E
H
G
E
P
G
S
G
L
I
D
V
E
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
I307
E
K
S
H
G
S
V
I
D
M
E
D
L
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
D310
M
D
V
I
D
V
E
D
L
G
S
V
M
N
K
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
T252
G
V
K
I
C
R
W
T
K
S
Q
L
R
G
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
V265
G
V
V
K
V
T
K
V
D
G
K
K
E
M
V
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
G388
E
D
E
E
E
G
N
G
S
D
E
L
G
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
81.1
77.3
N.A.
72.2
N.A.
N.A.
N.A.
63.2
63.9
62.3
N.A.
N.A.
N.A.
N.A.
48.1
Protein Similarity:
100
32.1
83.8
83.4
N.A.
81.1
N.A.
N.A.
N.A.
74
75.2
74.7
N.A.
N.A.
N.A.
N.A.
63.8
P-Site Identity:
100
0
93.3
0
N.A.
13.3
N.A.
N.A.
N.A.
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
0
93.3
26.6
N.A.
40
N.A.
N.A.
N.A.
33.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
42
N.A.
N.A.
41.4
29.8
N.A.
Protein Similarity:
57.1
N.A.
N.A.
57.7
46.3
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
0
25
0
9
9
17
9
17
9
9
42
0
% D
% Glu:
25
17
17
25
17
9
9
9
0
9
25
0
34
9
9
% E
% Phe:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
17
17
9
25
9
0
17
0
25
0
0
9
17
0
% G
% His:
0
0
0
17
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
0
0
9
0
0
0
25
0
0
0
% I
% Lys:
0
9
17
17
0
9
9
0
17
0
9
9
0
0
17
% K
% Leu:
0
0
0
0
0
9
0
0
25
0
9
17
9
0
17
% L
% Met:
9
0
0
0
0
0
0
0
0
9
0
0
9
9
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
17
0
0
0
9
9
% N
% Pro:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
9
0
0
17
0
0
0
9
9
0
0
0
% Q
% Arg:
0
0
0
0
0
17
9
0
0
0
0
0
9
0
9
% R
% Ser:
0
0
9
0
9
9
0
34
17
9
25
0
0
0
0
% S
% Thr:
0
0
0
0
0
17
9
9
0
0
0
0
0
0
0
% T
% Val:
0
25
17
0
9
9
9
9
17
17
0
25
17
9
34
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _