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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1B
All Species:
1.21
Human Site:
T333
Identified Species:
2.42
UniProt:
Q6NUM6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUM6
NP_001138912.1
668
76946
T333
R
E
R
S
L
L
Q
T
H
I
L
W
N
E
S
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
A57
Q
E
K
S
V
P
K
A
A
Q
D
L
M
T
N
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
K396
I
G
S
H
S
G
V
K
L
C
R
W
T
K
V
Dog
Lupus familis
XP_536836
714
81505
H379
G
R
G
G
C
Y
K
H
T
F
Y
G
I
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
H386
G
R
G
G
C
Y
K
H
T
F
Y
G
I
E
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
H406
G
R
G
G
C
Y
K
H
T
F
Y
G
I
E
S
Frog
Xenopus laevis
Q2KHP8
735
84095
H400
G
R
G
G
C
Y
K
H
T
F
Y
G
I
E
S
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
H395
G
R
G
G
C
Y
K
H
T
F
Y
G
I
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
H378
G
R
G
G
C
Y
K
H
T
F
Y
G
I
E
S
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
K307
V
G
K
S
W
Q
W
K
M
D
D
P
L
E
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
S329
R
C
M
E
T
T
P
S
L
A
C
A
N
K
C
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
K460
G
K
G
S
C
Y
K
K
S
L
F
N
I
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
81.1
77.3
N.A.
72.2
N.A.
N.A.
N.A.
63.2
63.9
62.3
N.A.
N.A.
N.A.
N.A.
48.1
Protein Similarity:
100
32.1
83.8
83.4
N.A.
81.1
N.A.
N.A.
N.A.
74
75.2
74.7
N.A.
N.A.
N.A.
N.A.
63.8
P-Site Identity:
100
13.3
6.6
13.3
N.A.
13.3
N.A.
N.A.
N.A.
13.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
46.6
13.3
20
N.A.
20
N.A.
N.A.
N.A.
20
20
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
42
N.A.
N.A.
41.4
29.8
N.A.
Protein Similarity:
57.1
N.A.
N.A.
57.7
46.3
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
9
9
0
9
0
9
0
% A
% Cys:
0
9
0
0
59
0
0
0
0
9
9
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
17
0
0
0
0
% D
% Glu:
0
17
0
9
0
0
0
0
0
0
0
0
0
67
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
50
9
0
0
0
0
% F
% Gly:
59
17
59
50
0
9
0
0
0
0
0
50
0
0
0
% G
% His:
0
0
0
9
0
0
0
50
9
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
0
0
59
0
9
% I
% Lys:
0
9
17
0
0
0
67
25
0
0
0
0
0
17
0
% K
% Leu:
0
0
0
0
9
9
0
0
17
9
9
9
9
0
0
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
9
17
0
9
% N
% Pro:
0
0
0
0
0
9
9
0
0
0
0
9
0
0
0
% P
% Gln:
9
0
0
0
0
9
9
0
0
9
0
0
0
0
0
% Q
% Arg:
17
50
9
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
9
34
9
0
0
9
9
0
0
0
0
0
67
% S
% Thr:
0
0
0
0
9
9
0
9
50
0
0
0
9
9
0
% T
% Val:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
9
0
9
0
0
0
0
17
0
0
0
% W
% Tyr:
0
0
0
0
0
59
0
0
0
0
50
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _