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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYW1B
All Species:
31.21
Human Site:
T347
Identified Species:
62.42
UniProt:
Q6NUM6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUM6
NP_001138912.1
668
76946
T347
S
H
R
C
M
E
T
T
P
S
L
A
C
A
N
Chimpanzee
Pan troglodytes
XP_001149962
340
38388
E71
N
G
Y
V
S
L
Q
E
K
D
I
F
V
S
G
Rhesus Macaque
Macaca mulatta
XP_001091335
749
86027
T410
V
F
F
L
C
L
L
T
G
R
G
G
C
F
K
Dog
Lupus familis
XP_536836
714
81505
T393
S
H
R
C
M
E
T
T
P
S
L
A
C
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJM7
721
81581
T400
S
H
R
C
M
E
A
T
P
S
L
A
C
A
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415726
741
84009
T420
S
H
R
C
M
E
A
T
P
S
L
A
C
A
N
Frog
Xenopus laevis
Q2KHP8
735
84095
T414
S
H
R
C
M
E
T
T
P
S
L
A
C
A
N
Zebra Danio
Brachydanio rerio
Q08C92
730
83531
T409
S
H
R
C
M
E
T
T
P
S
L
A
C
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188746
713
80418
T392
S
H
R
C
M
E
T
T
P
S
L
A
C
A
N
Poplar Tree
Populus trichocarpa
XP_002301868
592
66250
L321
I
V
N
S
A
I
D
L
H
T
K
M
I
K
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RXN5
647
72062
H343
C
V
F
C
W
R
H
H
T
N
P
V
G
K
S
Baker's Yeast
Sacchar. cerevisiae
Q08960
810
89787
T474
S
S
R
C
M
E
L
T
P
S
L
A
C
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
81.1
77.3
N.A.
72.2
N.A.
N.A.
N.A.
63.2
63.9
62.3
N.A.
N.A.
N.A.
N.A.
48.1
Protein Similarity:
100
32.1
83.8
83.4
N.A.
81.1
N.A.
N.A.
N.A.
74
75.2
74.7
N.A.
N.A.
N.A.
N.A.
63.8
P-Site Identity:
100
0
13.3
100
N.A.
93.3
N.A.
N.A.
N.A.
93.3
100
100
N.A.
N.A.
N.A.
N.A.
100
P-Site Similarity:
100
20
13.3
100
N.A.
93.3
N.A.
N.A.
N.A.
93.3
100
100
N.A.
N.A.
N.A.
N.A.
100
Percent
Protein Identity:
42
N.A.
N.A.
41.4
29.8
N.A.
Protein Similarity:
57.1
N.A.
N.A.
57.7
46.3
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
73.3
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
20
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
17
0
0
0
0
67
0
59
0
% A
% Cys:
9
0
0
75
9
0
0
0
0
0
0
0
75
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
67
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
9
17
0
0
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
0
9
0
0
0
0
0
0
9
0
9
9
9
0
9
% G
% His:
0
59
0
0
0
0
9
9
9
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
9
0
0
0
0
9
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
9
0
0
17
9
% K
% Leu:
0
0
0
9
0
17
17
9
0
0
67
0
0
0
0
% L
% Met:
0
0
0
0
67
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
9
0
0
0
0
59
% N
% Pro:
0
0
0
0
0
0
0
0
67
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
67
0
0
9
0
0
0
9
0
0
0
0
0
% R
% Ser:
67
9
0
9
9
0
0
0
0
67
0
0
0
17
17
% S
% Thr:
0
0
0
0
0
0
42
75
9
9
0
0
0
0
0
% T
% Val:
9
17
0
9
0
0
0
0
0
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _