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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RETSAT
All Species:
6.06
Human Site:
Y412
Identified Species:
12.12
UniProt:
Q6NUM9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUM9
NP_060220.3
610
66820
Y412
S
T
N
Y
Y
V
Y
Y
D
T
D
M
D
Q
A
Chimpanzee
Pan troglodytes
XP_525801
610
66788
Y412
S
T
N
Y
Y
V
Y
Y
D
T
D
M
D
Q
A
Rhesus Macaque
Macaca mulatta
XP_001083594
610
66987
H412
S
T
N
Y
Y
V
Y
H
D
T
D
M
D
Q
A
Dog
Lupus familis
XP_540198
608
66944
F410
S
T
N
Y
F
V
C
F
D
T
D
L
D
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q64FW2
609
67445
F411
S
T
N
Y
Y
V
Y
F
D
T
D
M
D
K
A
Rat
Rattus norvegicus
Q8VHE9
609
67512
F411
S
T
N
Y
Y
V
Y
F
D
T
D
M
D
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518480
365
41018
G175
C
P
S
W
R
D
R
G
R
A
G
F
Q
P
S
Chicken
Gallus gallus
XP_424187
305
34045
T115
Q
S
R
L
R
M
A
T
H
G
E
G
G
F
S
Frog
Xenopus laevis
NP_001116352
608
67274
P408
G
A
N
Y
I
Y
F
P
D
T
N
L
E
M
L
Zebra Danio
Brachydanio rerio
Q5BLE8
607
67919
P407
A
D
N
Y
F
I
Y
P
E
N
N
I
D
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786388
583
65117
K383
L
L
P
L
E
I
V
K
K
H
D
L
M
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9Y8
595
65410
S390
K
V
Y
V
K
A
P
S
F
L
S
I
H
M
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
94.5
81.4
N.A.
80.6
80.4
N.A.
25.8
29.6
51.6
49.1
N.A.
N.A.
N.A.
N.A.
42.3
Protein Similarity:
100
100
97.5
89.6
N.A.
91.1
90.9
N.A.
38.2
37.7
71.1
69.1
N.A.
N.A.
N.A.
N.A.
59.5
P-Site Identity:
100
100
93.3
66.6
N.A.
86.6
86.6
N.A.
0
0
26.6
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
20
26.6
53.3
73.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
9
9
0
0
9
0
0
0
0
50
% A
% Cys:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
0
0
59
0
59
0
59
9
0
% D
% Glu:
0
0
0
0
9
0
0
0
9
0
9
0
9
9
0
% E
% Phe:
0
0
0
0
17
0
9
25
9
0
0
9
0
9
0
% F
% Gly:
9
0
0
0
0
0
0
9
0
9
9
9
9
0
9
% G
% His:
0
0
0
0
0
0
0
9
9
9
0
0
9
0
0
% H
% Ile:
0
0
0
0
9
17
0
0
0
0
0
17
0
0
0
% I
% Lys:
9
0
0
0
9
0
0
9
9
0
0
0
0
25
9
% K
% Leu:
9
9
0
17
0
0
0
0
0
9
0
25
0
0
17
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
42
9
17
0
% M
% Asn:
0
0
67
0
0
0
0
0
0
9
17
0
0
0
0
% N
% Pro:
0
9
9
0
0
0
9
17
0
0
0
0
0
9
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
9
25
0
% Q
% Arg:
0
0
9
0
17
0
9
0
9
0
0
0
0
0
0
% R
% Ser:
50
9
9
0
0
0
0
9
0
0
9
0
0
0
17
% S
% Thr:
0
50
0
0
0
0
0
9
0
59
0
0
0
0
0
% T
% Val:
0
9
0
9
0
50
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
67
42
9
50
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _