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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM214 All Species: 8.18
Human Site: S595 Identified Species: 18
UniProt: Q6NUQ4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NUQ4 NP_060197.4 689 77151 S595 G D S L T S L S Q R L Q I Q L
Chimpanzee Pan troglodytes XP_001153665 689 77137 S595 G D S L T S L S Q R L Q I Q L
Rhesus Macaque Macaca mulatta XP_001088228 597 66501 A528 P A S Q Q A C A K L Y S Y S L
Dog Lupus familis XP_853692 656 73702 S564 G D S L A S L S Q R L Q V P D
Cat Felis silvestris
Mouse Mus musculus Q8BM55 687 76411 F595 S D S L A G F F Q R V Q L P E
Rat Rattus norvegicus A1L1L2 685 76548 L593 S D S L A G V L Q R V Q L P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426216 680 75753 L586 G E R L P W L L E W L Q S R L
Frog Xenopus laevis A1L2I9 679 76789 I585 K D N L P R L I E W L H S S I
Zebra Danio Brachydanio rerio XP_700034 672 76079 L580 Q E N L P L L L H W I H A N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788023 677 75663 V605 A K F I D Q Y V P N S S G K I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190838 459 53200 V391 D W I L A Q T V E I L Q R L M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 84.9 84.6 N.A. 81.4 82.2 N.A. N.A. 57.7 53.7 53.5 N.A. 22.5 N.A. N.A. 25.6
Protein Similarity: 100 98.9 85.4 88.5 N.A. 87.8 89.2 N.A. N.A. 73 71.1 70.5 N.A. 41.6 N.A. N.A. 38.9
P-Site Identity: 100 100 13.3 73.3 N.A. 40 40 N.A. N.A. 40 26.6 13.3 N.A. 0 N.A. N.A. 20
P-Site Similarity: 100 100 33.3 80 N.A. 53.3 60 N.A. N.A. 60 46.6 33.3 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 37 10 0 10 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 10 55 0 0 10 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 19 0 0 0 0 0 0 28 0 0 0 0 0 19 % E
% Phe: 0 0 10 0 0 0 10 10 0 0 0 0 0 0 0 % F
% Gly: 37 0 0 0 0 19 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 19 0 0 0 % H
% Ile: 0 0 10 10 0 0 0 10 0 10 10 0 19 0 19 % I
% Lys: 10 10 0 0 0 0 0 0 10 0 0 0 0 10 0 % K
% Leu: 0 0 0 82 0 10 55 28 0 10 55 0 19 10 37 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 19 0 0 0 0 0 0 10 0 0 0 10 0 % N
% Pro: 10 0 0 0 28 0 0 0 10 0 0 0 0 28 0 % P
% Gln: 10 0 0 10 10 19 0 0 46 0 0 64 0 19 0 % Q
% Arg: 0 0 10 0 0 10 0 0 0 46 0 0 10 10 0 % R
% Ser: 19 0 55 0 0 28 0 28 0 0 10 19 19 19 0 % S
% Thr: 0 0 0 0 19 0 10 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 10 19 0 0 19 0 10 0 0 % V
% Trp: 0 10 0 0 0 10 0 0 0 28 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _