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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM214
All Species:
29.39
Human Site:
T374
Identified Species:
64.67
UniProt:
Q6NUQ4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUQ4
NP_060197.4
689
77151
T374
P
S
F
L
S
R
A
T
P
S
C
P
P
E
M
Chimpanzee
Pan troglodytes
XP_001153665
689
77137
T374
P
S
F
L
S
R
A
T
P
S
C
P
P
E
M
Rhesus Macaque
Macaca mulatta
XP_001088228
597
66501
D317
F
G
M
I
G
P
K
D
F
F
P
L
L
D
F
Dog
Lupus familis
XP_853692
656
73702
T343
P
S
F
L
S
R
A
T
P
S
C
P
P
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM55
687
76411
T374
P
S
F
L
S
R
A
T
P
S
C
P
A
A
M
Rat
Rattus norvegicus
A1L1L2
685
76548
T372
P
S
F
L
S
R
A
T
P
S
C
P
A
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426216
680
75753
T365
P
S
F
L
S
R
A
T
P
S
C
P
P
A
M
Frog
Xenopus laevis
A1L2I9
679
76789
T365
P
S
F
L
S
R
A
T
P
S
C
P
A
E
M
Zebra Danio
Brachydanio rerio
XP_700034
672
76079
T361
P
S
F
L
S
R
A
T
P
N
C
P
G
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788023
677
75663
Q371
E
I
S
A
G
S
K
Q
T
N
E
I
E
G
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190838
459
53200
L180
L
E
C
L
V
F
C
L
C
Q
D
Q
H
C
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
84.9
84.6
N.A.
81.4
82.2
N.A.
N.A.
57.7
53.7
53.5
N.A.
22.5
N.A.
N.A.
25.6
Protein Similarity:
100
98.9
85.4
88.5
N.A.
87.8
89.2
N.A.
N.A.
73
71.1
70.5
N.A.
41.6
N.A.
N.A.
38.9
P-Site Identity:
100
100
0
100
N.A.
86.6
86.6
N.A.
N.A.
93.3
93.3
80
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
86.6
86.6
N.A.
N.A.
93.3
93.3
86.6
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
73
0
0
0
0
0
28
37
0
% A
% Cys:
0
0
10
0
0
0
10
0
10
0
73
0
0
10
10
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
0
0
10
0
% D
% Glu:
10
10
0
0
0
0
0
0
0
0
10
0
10
37
0
% E
% Phe:
10
0
73
0
0
10
0
0
10
10
0
0
0
0
19
% F
% Gly:
0
10
0
0
19
0
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
0
10
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
82
0
0
0
10
0
0
0
10
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
73
% M
% Asn:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% N
% Pro:
73
0
0
0
0
10
0
0
73
0
10
73
37
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
73
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
73
10
0
73
10
0
0
0
64
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
73
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _