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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM214
All Species:
29.09
Human Site:
Y407
Identified Species:
64
UniProt:
Q6NUQ4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUQ4
NP_060197.4
689
77151
Y407
A
S
V
W
R
Q
L
Y
P
K
H
L
S
Q
S
Chimpanzee
Pan troglodytes
XP_001153665
689
77137
Y407
A
S
V
W
R
Q
L
Y
P
K
H
L
S
Q
S
Rhesus Macaque
Macaca mulatta
XP_001088228
597
66501
L350
L
Y
P
R
L
K
V
L
A
F
G
A
K
P
D
Dog
Lupus familis
XP_853692
656
73702
Y376
A
S
V
W
R
Q
L
Y
P
K
H
L
S
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BM55
687
76411
Y407
T
S
V
W
R
Q
L
Y
P
K
H
L
S
Q
S
Rat
Rattus norvegicus
A1L1L2
685
76548
Y405
T
S
V
W
R
Q
L
Y
P
K
H
L
S
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426216
680
75753
Y398
F
S
V
W
R
Q
L
Y
T
K
H
L
S
Q
S
Frog
Xenopus laevis
A1L2I9
679
76789
Y398
F
S
V
W
R
Q
L
Y
T
K
H
L
S
Q
S
Zebra Danio
Brachydanio rerio
XP_700034
672
76079
Y394
L
S
V
W
R
Q
L
Y
T
K
H
L
P
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788023
677
75663
P404
N
Y
K
K
Q
Q
L
P
S
L
L
L
L
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190838
459
53200
D213
N
H
I
I
K
V
W
D
Q
V
K
L
P
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
84.9
84.6
N.A.
81.4
82.2
N.A.
N.A.
57.7
53.7
53.5
N.A.
22.5
N.A.
N.A.
25.6
Protein Similarity:
100
98.9
85.4
88.5
N.A.
87.8
89.2
N.A.
N.A.
73
71.1
70.5
N.A.
41.6
N.A.
N.A.
38.9
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
80
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
80
N.A.
40
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
0
0
0
0
0
0
0
10
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
19
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
73
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
10
10
0
0
0
73
10
0
10
19
10
% K
% Leu:
19
0
0
0
10
0
82
10
0
10
10
91
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
10
46
0
0
0
19
10
0
% P
% Gln:
0
0
0
0
10
82
0
0
10
0
0
0
0
73
0
% Q
% Arg:
0
0
0
10
73
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
73
0
0
0
0
0
0
10
0
0
0
64
0
73
% S
% Thr:
19
0
0
0
0
0
0
0
28
0
0
0
0
0
0
% T
% Val:
0
0
73
0
0
10
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
73
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _