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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPY19L2
All Species:
9.39
Human Site:
S451
Identified Species:
22.96
UniProt:
Q6NUT2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUT2
NP_776173.3
758
87374
S451
T
S
K
I
L
G
V
S
D
H
I
R
L
S
D
Chimpanzee
Pan troglodytes
XP_001165093
758
87247
S451
T
S
K
I
L
G
V
S
D
H
I
R
L
S
D
Rhesus Macaque
Macaca mulatta
XP_001105350
677
77367
S382
L
L
T
S
K
F
F
S
Y
K
D
F
D
T
L
Dog
Lupus familis
XP_532514
734
84800
R439
L
S
D
L
I
A
A
R
I
L
R
Y
T
D
F
Cat
Felis silvestris
Mouse
Mus musculus
A6X919
746
84169
L444
D
D
A
H
I
G
N
L
L
T
S
K
F
F
S
Rat
Rattus norvegicus
XP_002727076
852
98229
S545
T
S
K
I
C
G
V
S
D
H
I
R
L
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508949
256
29083
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394017
691
79722
E396
M
L
Y
T
C
S
P
E
F
D
F
L
Q
Y
R
Nematode Worm
Caenorhab. elegans
P34413
683
77833
A388
R
S
K
F
T
S
F
A
N
F
H
T
R
L
Y
Sea Urchin
Strong. purpuratus
XP_785579
669
76751
Q374
A
A
E
F
D
F
M
Q
N
E
T
V
I
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
59.7
82
N.A.
60.4
69.5
N.A.
24.4
N.A.
N.A.
N.A.
N.A.
N.A.
34.4
36.1
42.4
Protein Similarity:
100
99.8
72.8
88.2
N.A.
75
77.2
N.A.
29.6
N.A.
N.A.
N.A.
N.A.
N.A.
54
56.2
59.8
P-Site Identity:
100
100
6.6
6.6
N.A.
6.6
93.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
13.3
0
P-Site Similarity:
100
100
13.3
20
N.A.
20
93.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
10
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
0
10
0
0
0
30
10
10
0
10
10
30
% D
% Glu:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
20
0
20
20
0
10
10
10
10
10
10
20
% F
% Gly:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
30
10
0
0
0
0
% H
% Ile:
0
0
0
30
20
0
0
0
10
0
30
0
10
0
0
% I
% Lys:
0
0
40
0
10
0
0
0
0
10
0
10
0
10
0
% K
% Leu:
20
20
0
10
20
0
0
10
10
10
0
10
30
10
10
% L
% Met:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
20
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
0
0
0
10
0
0
10
30
10
0
10
% R
% Ser:
0
50
0
10
0
20
0
40
0
0
10
0
0
30
10
% S
% Thr:
30
0
10
10
10
0
0
0
0
10
10
10
10
10
0
% T
% Val:
0
0
0
0
0
0
30
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
10
0
0
10
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _