KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPY19L2
All Species:
10.3
Human Site:
T145
Identified Species:
25.19
UniProt:
Q6NUT2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUT2
NP_776173.3
758
87374
T145
S
S
L
E
R
E
M
T
F
R
T
E
M
G
L
Chimpanzee
Pan troglodytes
XP_001165093
758
87247
T145
S
S
L
E
R
E
M
T
F
R
T
E
M
G
L
Rhesus Macaque
Macaca mulatta
XP_001105350
677
77367
F82
T
I
V
E
A
P
S
F
L
N
G
V
W
M
I
Dog
Lupus familis
XP_532514
734
84800
A139
Y
F
K
T
I
I
E
A
P
S
F
L
K
G
L
Cat
Felis silvestris
Mouse
Mus musculus
A6X919
746
84169
K143
G
L
Y
Y
S
Y
F
K
T
I
V
E
A
P
S
Rat
Rattus norvegicus
XP_002727076
852
98229
T239
S
S
L
E
R
E
M
T
F
R
T
E
M
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508949
256
29083
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394017
691
79722
I96
R
K
I
S
H
D
N
I
S
E
Y
G
N
V
I
Nematode Worm
Caenorhab. elegans
P34413
683
77833
F88
T
I
I
N
A
P
S
F
L
E
G
V
Q
E
I
Sea Urchin
Strong. purpuratus
XP_785579
669
76751
T74
N
V
T
E
Y
P
S
T
I
N
T
L
K
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
59.7
82
N.A.
60.4
69.5
N.A.
24.4
N.A.
N.A.
N.A.
N.A.
N.A.
34.4
36.1
42.4
Protein Similarity:
100
99.8
72.8
88.2
N.A.
75
77.2
N.A.
29.6
N.A.
N.A.
N.A.
N.A.
N.A.
54
56.2
59.8
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
0
20
P-Site Similarity:
100
100
26.6
13.3
N.A.
6.6
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
0
10
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
50
0
30
10
0
0
20
0
40
0
10
0
% E
% Phe:
0
10
0
0
0
0
10
20
30
0
10
0
0
0
10
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
20
10
0
40
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
20
0
10
10
0
10
10
10
0
0
0
0
30
% I
% Lys:
0
10
10
0
0
0
0
10
0
0
0
0
20
0
0
% K
% Leu:
0
10
30
0
0
0
0
0
20
0
0
20
0
0
40
% L
% Met:
0
0
0
0
0
0
30
0
0
0
0
0
30
10
0
% M
% Asn:
10
0
0
10
0
0
10
0
0
20
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
30
0
0
10
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
30
0
0
0
0
30
0
0
0
10
0
% R
% Ser:
30
30
0
10
10
0
30
0
10
10
0
0
0
0
10
% S
% Thr:
20
0
10
10
0
0
0
40
10
0
40
0
0
0
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
10
20
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
10
0
10
10
10
10
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _