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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPY19L2
All Species:
8.48
Human Site:
Y397
Identified Species:
20.74
UniProt:
Q6NUT2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUT2
NP_776173.3
758
87374
Y397
N
S
M
Y
L
S
S
Y
Y
S
S
S
L
L
M
Chimpanzee
Pan troglodytes
XP_001165093
758
87247
Y397
N
S
M
Y
L
S
S
Y
Y
S
S
S
L
L
M
Rhesus Macaque
Macaca mulatta
XP_001105350
677
77367
P329
W
G
I
L
A
M
K
P
H
F
L
K
I
N
V
Dog
Lupus familis
XP_532514
734
84800
L386
L
M
T
L
V
I
I
L
K
R
N
K
I
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
A6X919
746
84169
W391
A
S
S
L
V
I
I
W
G
M
L
A
M
K
P
Rat
Rattus norvegicus
XP_002727076
852
98229
Y491
N
P
M
Y
L
S
S
Y
Y
S
S
C
L
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508949
256
29083
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394017
691
79722
Q343
K
F
I
G
T
K
L
Q
T
F
L
E
I
V
F
Nematode Worm
Caenorhab. elegans
P34413
683
77833
L335
M
I
I
Y
I
S
P
L
L
S
N
L
K
F
R
Sea Urchin
Strong. purpuratus
XP_785579
669
76751
L321
I
W
I
C
Q
L
C
L
L
F
G
G
T
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
59.7
82
N.A.
60.4
69.5
N.A.
24.4
N.A.
N.A.
N.A.
N.A.
N.A.
34.4
36.1
42.4
Protein Similarity:
100
99.8
72.8
88.2
N.A.
75
77.2
N.A.
29.6
N.A.
N.A.
N.A.
N.A.
N.A.
54
56.2
59.8
P-Site Identity:
100
100
0
0
N.A.
6.6
73.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
20
6.6
P-Site Similarity:
100
100
26.6
20
N.A.
33.3
86.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
20
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
10
0
0
10
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
30
0
0
0
10
10
% F
% Gly:
0
10
0
10
0
0
0
0
10
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
10
40
0
10
20
20
0
0
0
0
0
30
10
0
% I
% Lys:
10
0
0
0
0
10
10
0
10
0
0
20
10
10
0
% K
% Leu:
10
0
0
30
30
10
10
30
20
0
30
10
30
30
0
% L
% Met:
10
10
30
0
0
10
0
0
0
10
0
0
10
0
20
% M
% Asn:
30
0
0
0
0
0
0
0
0
0
20
0
0
10
0
% N
% Pro:
0
10
0
0
0
0
10
10
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
20
% R
% Ser:
0
30
10
0
0
40
30
0
0
40
30
20
0
0
0
% S
% Thr:
0
0
10
0
10
0
0
0
10
0
0
0
10
0
0
% T
% Val:
0
0
0
0
20
0
0
0
0
0
0
0
0
10
30
% V
% Trp:
10
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
40
0
0
0
30
30
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _