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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPY19L2 All Species: 9.39
Human Site: Y525 Identified Species: 22.96
UniProt: Q6NUT2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NUT2 NP_776173.3 758 87374 Y525 Y V L A T N I Y L R K Q L L E
Chimpanzee Pan troglodytes XP_001165093 758 87247 Y525 Y V L A T N I Y L R K Q L L E
Rhesus Macaque Macaca mulatta XP_001105350 677 77367 H456 D H G E L V Y H A L Q L L A Y
Dog Lupus familis XP_532514 734 84800 I513 L L E H G E L I F H T L Q L L
Cat Felis silvestris
Mouse Mus musculus A6X919 746 84169 E518 H T R K Q Q F E H G E L V Y H
Rat Rattus norvegicus XP_002727076 852 98229 Y619 C V L Y T N T Y Q R K Q L L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508949 256 29083 T35 F D F M E K E T P L R Y T K T
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394017 691 79722 N470 M R L K L F M N P H L C I I A
Nematode Worm Caenorhab. elegans P34413 683 77833 S462 N V V Q L C C S T V M A F L I
Sea Urchin Strong. purpuratus XP_785579 669 76751 L448 R Q L P N A E L V Y H L L Q L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 59.7 82 N.A. 60.4 69.5 N.A. 24.4 N.A. N.A. N.A. N.A. N.A. 34.4 36.1 42.4
Protein Similarity: 100 99.8 72.8 88.2 N.A. 75 77.2 N.A. 29.6 N.A. N.A. N.A. N.A. N.A. 54 56.2 59.8
P-Site Identity: 100 100 6.6 6.6 N.A. 0 66.6 N.A. 0 N.A. N.A. N.A. N.A. N.A. 6.6 13.3 13.3
P-Site Similarity: 100 100 20 20 N.A. 20 73.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. 26.6 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 20 0 10 0 0 10 0 0 10 0 10 10 % A
% Cys: 10 0 0 0 0 10 10 0 0 0 0 10 0 0 0 % C
% Asp: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 10 10 10 10 20 10 0 0 10 0 0 0 20 % E
% Phe: 10 0 10 0 0 10 10 0 10 0 0 0 10 0 0 % F
% Gly: 0 0 10 0 10 0 0 0 0 10 0 0 0 0 0 % G
% His: 10 10 0 10 0 0 0 10 10 20 10 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 20 10 0 0 0 0 10 10 10 % I
% Lys: 0 0 0 20 0 10 0 0 0 0 30 0 0 10 0 % K
% Leu: 10 10 50 0 30 0 10 10 20 20 10 40 50 50 20 % L
% Met: 10 0 0 10 0 0 10 0 0 0 10 0 0 0 0 % M
% Asn: 10 0 0 0 10 30 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 20 0 0 0 0 0 0 % P
% Gln: 0 10 0 10 10 10 0 0 10 0 10 30 10 10 0 % Q
% Arg: 10 10 10 0 0 0 0 0 0 30 10 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % S
% Thr: 0 10 0 0 30 0 10 10 10 0 10 0 10 0 10 % T
% Val: 0 40 10 0 0 10 0 0 10 10 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 20 0 0 10 0 0 10 30 0 10 0 10 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _