Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIPAL1 All Species: 14.85
Human Site: T370 Identified Species: 36.3
UniProt: Q6NVV3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NVV3 NP_997213.1 410 44638 T370 T W S E L T S T A K K E A V S
Chimpanzee Pan troglodytes XP_001158930 359 39038 A319 S F R K D E K A M N G N L S N
Rhesus Macaque Macaca mulatta XP_001102883 410 44527 T370 T W S E L T S T A K K E A I S
Dog Lupus familis XP_539257 478 51733 T435 T W S D L T S T T Q K E V L S
Cat Felis silvestris
Mouse Mus musculus Q8BMW7 416 45140 T370 T W S E L M S T A K K E A L S
Rat Rattus norvegicus NP_001099473 397 42686 S358 T A K K E V L S S N G S Q N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515422 341 36461 V302 S A P V R K G V A S A L S A G
Chicken Gallus gallus NP_001025980 361 39089 G322 K D D R A A N G S L L S T Y D
Frog Xenopus laevis NP_001086011 362 39221 S323 D E R T L N G S L S N N I Y E
Zebra Danio Brachydanio rerio NP_998290 367 39660 A328 P V S N G M A A H N H S N Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.5 98.5 77.6 N.A. 85.8 84.6 N.A. 58.2 58 58.2 58.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.9 99.2 80.5 N.A. 91.3 89 N.A. 70.2 69.2 70.2 70.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 66.6 N.A. 86.6 13.3 N.A. 6.6 0 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 86.6 N.A. 93.3 33.3 N.A. 20 13.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 10 10 10 20 40 0 10 0 30 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 10 10 10 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 10 0 30 10 10 0 0 0 0 0 40 0 0 20 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 20 10 0 0 20 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % I
% Lys: 10 0 10 20 0 10 10 0 0 30 40 0 0 0 0 % K
% Leu: 0 0 0 0 50 0 10 0 10 10 10 10 10 20 0 % L
% Met: 0 0 0 0 0 20 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 10 10 0 0 30 10 20 10 10 10 % N
% Pro: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % Q
% Arg: 0 0 20 10 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 20 0 50 0 0 0 40 20 20 20 0 30 10 10 50 % S
% Thr: 50 0 0 10 0 30 0 40 10 0 0 0 10 0 0 % T
% Val: 0 10 0 10 0 10 0 10 0 0 0 0 10 10 0 % V
% Trp: 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _