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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIPAL1 All Species: 13.94
Human Site: Y385 Identified Species: 34.07
UniProt: Q6NVV3 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.44
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NVV3 NP_997213.1 410 44638 Y385 L N V N E N N Y V L L E N L E
Chimpanzee Pan troglodytes XP_001158930 359 39038 D334 M Y E V L N N D E S L T C G I
Rhesus Macaque Macaca mulatta XP_001102883 410 44527 Y385 L N V N E N N Y V L L E N L E
Dog Lupus familis XP_539257 478 51733 Y450 L N G N E D K Y V L L E N T E
Cat Felis silvestris
Mouse Mus musculus Q8BMW7 416 45140 Y385 P N G N Q N S Y V L L E N A D
Rat Rattus norvegicus NP_001099473 397 42686 D373 Y V L L E N A D C S T S G C D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515422 341 36461 E317 E D G H A L L E H V E C S R L
Chicken Gallus gallus NP_001025980 361 39089 S337 C F N H D E E S S T C V S E I
Frog Xenopus laevis NP_001086011 362 39221 S338 H L N G D E E S E L S D S E L
Zebra Danio Brachydanio rerio NP_998290 367 39660 E343 L L R N E V T E D F E D R E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.5 98.5 77.6 N.A. 85.8 84.6 N.A. 58.2 58 58.2 58.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.9 99.2 80.5 N.A. 91.3 89 N.A. 70.2 69.2 70.2 70.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 100 73.3 N.A. 60 13.3 N.A. 0 0 6.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 80 N.A. 80 26.6 N.A. 26.6 20 26.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 10 0 0 0 0 0 0 10 0 % A
% Cys: 10 0 0 0 0 0 0 0 10 0 10 10 10 10 0 % C
% Asp: 0 10 0 0 20 10 0 20 10 0 0 20 0 0 20 % D
% Glu: 10 0 10 0 50 20 20 20 20 0 20 40 0 30 30 % E
% Phe: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 30 10 0 0 0 0 0 0 0 0 10 10 0 % G
% His: 10 0 0 20 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 40 20 10 10 10 10 10 0 0 50 50 0 0 20 20 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 40 20 50 0 50 30 0 0 0 0 0 40 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 10 10 0 % R
% Ser: 0 0 0 0 0 0 10 20 10 20 10 10 30 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 10 10 10 0 10 0 % T
% Val: 0 10 20 10 0 10 0 0 40 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 10 0 0 0 0 0 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _