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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM5P
All Species:
3.64
Human Site:
S277
Identified Species:
13.33
UniProt:
Q6NVV9
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NVV9
NP_055052
412
47181
S277
W
E
H
R
D
L
I
S
R
P
N
L
S
V
I
Chimpanzee
Pan troglodytes
XP_519721
739
82738
K558
L
A
C
V
Q
P
H
K
N
A
N
K
S
E
V
Rhesus Macaque
Macaca mulatta
XP_001095172
855
95089
H630
Y
P
T
R
K
P
F
H
Q
E
N
G
D
V
I
Dog
Lupus familis
XP_539964
771
86470
S557
W
P
H
K
A
L
V
S
R
A
N
L
S
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3TTE0
751
84516
L554
W
P
F
K
K
L
V
L
K
A
N
L
S
V
A
Rat
Rattus norvegicus
Q5BK84
709
79889
M512
W
P
F
K
R
L
L
M
K
D
N
M
S
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517248
508
56773
H345
Y
P
S
Q
T
P
F
H
I
L
N
A
S
V
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.6
21.5
31.2
N.A.
28.5
27.5
N.A.
21.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.8
32.1
41.1
N.A.
39.9
39.9
N.A.
37.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
26.6
66.6
N.A.
40
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
40
80
N.A.
60
53.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
15
0
0
0
0
43
0
15
0
15
29
% A
% Cys:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
0
0
0
0
15
0
0
15
0
0
% D
% Glu:
0
15
0
0
0
0
0
0
0
15
0
0
0
15
0
% E
% Phe:
0
0
29
0
0
0
29
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% G
% His:
0
0
29
0
0
0
15
29
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
15
0
15
0
0
0
0
0
58
% I
% Lys:
0
0
0
43
29
0
0
15
29
0
0
15
0
0
0
% K
% Leu:
15
0
0
0
0
58
15
15
0
15
0
43
0
0
0
% L
% Met:
0
0
0
0
0
0
0
15
0
0
0
15
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
15
0
100
0
0
0
0
% N
% Pro:
0
72
0
0
0
43
0
0
0
15
0
0
0
0
0
% P
% Gln:
0
0
0
15
15
0
0
0
15
0
0
0
0
0
0
% Q
% Arg:
0
0
0
29
15
0
0
0
29
0
0
0
0
0
0
% R
% Ser:
0
0
15
0
0
0
0
29
0
0
0
0
86
0
0
% S
% Thr:
0
0
15
0
15
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
15
0
0
29
0
0
0
0
0
0
72
15
% V
% Trp:
58
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
29
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _